Review Article

Self-Eating: Friend or Foe? The Emerging Role of Autophagy in Idiopathic Pulmonary Fibrosis

Table 2

Clinical trials targeting autophagy in pulmonary diseases.

IdentifierConditionInterventionPhaseStatus

NCT00969306SCLCChloroquine, A-CQ100Phase 1Not yet recruiting
NCT00933803NSCLCPaclitaxel
Carboplatin
Hydroxychloroquine
Bevacizumab
Phase 1
Phase 2
Active
Not recruiting
NCT01649947NSCLC
Recurrent
NSCLC
Paclitaxel
Carboplatin
Hydroxychloroquine
Bevacizumab
Phase 2Recruiting
NCT00728845Recurrent
Advanced
NSCLC
Bevacizumab
Carboplatin
Hydroxychloroquine
Paclitaxel
Phase 1
Phase 2
Terminated
NCT01687179LAMSirolimus and hydroxychloroquinePhase 1Recruiting

SCLC: small-cell lung cancer, NSCLC: non-small cell lung cancer, LAM: lymphangioleiomyomatosis.