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BioMed Research International
Volume 2013 (2013), Article ID 426709, 9 pages
http://dx.doi.org/10.1155/2013/426709
Review Article

Emergence in Western African Countries of MDR-TB, Focus on Côte d’Ivoire

1Département de Bactériologie-Virologie, Institut Pasteur de Côte d’Ivoire, 01 BP 490 Abidjan 01, Cote D'Ivoire
2Thérapeutiques Cliniques et Expérimentales des Infections, Département des Maladies Infectieuses UFR de Médecine, 1, rue Gaston Veil, 44035 Nantes Cedex, France
3Programme National de Lutte Contre la Tuberculose, 05 BP 1054 Abidjan 05, Cote D'Ivoire
4Biofortis Research, Biofortis SAS, Mérieux Nutriscience Company, 3 route de la Chatterie, 44800 Saint-Herblain, France
5INSERM-Unité 892—CNRS 6299, 8 quai Moncousu, BP 70721, 44007 Nantes Cedex 1, France
6INSERM, Thérapeutiques Cliniques et Expérimentales des Infections, Département des Maladies Infectieuses UFR de Médecine, 1, rue Gaston Veil, 44035 Nantes Cedex, France

Received 15 April 2013; Revised 28 July 2013; Accepted 28 July 2013

Academic Editor: Lucia Lopalco

Copyright © 2013 Euloge Ekaza et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Tuberculosis (TB) is responsible for a high mortality rate (2.5%) worldwide, mainly in developing countries with a high prevalence of human immunodeficiency virus (HIV). The emergence of multiresistant strains of TB poses an extreme risk for TB outbreaks and highlights the need for global TB control strategies. Among Western African countries, Côte d’Ivoire (CI) represents a specific example of a country with great potential to prevent TB. Specifically, CI has a promising healthcare system for monitoring diseases, including vaccination programs. However, military and political conflict in CI favors the spread of infectious diseases, TB being among the most devastating. Compilation of the studies identifying common causes of TB would be extremely beneficial for the development of treatment and prevention strategies. Therefore, the purpose of this comprehensive review is to evaluate the epidemiology of TB in CI, describe the factors involved in pathogenesis, and suggest simple and applicable prevention strategies.