Table 1: Effects of fasudil on body weight, heart weight, blood pressure, blood glucose, serum insulin, glycated hemoglobin, and lipid profiles in diabetic rats either treated with or without fasudil.

Fasudil-treated diabetic group ( )Untreated diabetic group ( )Control group
( )

Start weight (g)191 ± 7190 ± 8192 ± 7
End weight (g)465 ± 9#442 ± 10*465 ± 10
Heart weight (g)1.72 ± 0.111.68 ± 0.09*1.78 ± 0.06
Mean blood pressure (kpa)8.21 ± 1.219.44 ± 1.598.43 ± 1.25
Fasting blood glucose (mmol/L)20.0 ± 2.6*19.9 ± 2.4*6.1 ± 0.2
Serum insulin (ng/mL)6.17 ± 0.99*5.97 ± 1.00*4.78 ± 0.67
Glycated hemoglobin (%)13.4 ± 1.7*12.5 ± 1.8*4.9 ± 0.4
Total cholesterol (mmol/L)1.41 ± 0.15*1.40 ± 0.13*0.95 ± 0.12
Triglyceride (mmol/L)0.63 ± 0.100.61 ± 0.080.55 ± 0.06
Free fatty acids (mmol/L)0.33 ± 0.060.40 ± 0.18*0.28 ± 0.07

Data are presented as the mean ± SD.
* versus control group.
# versus untreated diabetic group.