Research Article
Association between Polymorphisms of Alpha-Adducin Gene and Essential Hypertension in Chinese Population
Table 2
Association analysis of 6 tagSNPs.
| | SNP | Group | Genotype | value | OR | 95% CI |
| | rs16843452 | Hypertensive | 243 (CC) | 462 (CT) | 195 (TT) | 0.89 | 1.01 | 0.89~1.15 | | Control | 243 (CC) | 461 (CT) | 199 (TT) | | rs12503220 | Hypertensive | 11 (AA) | 253 (AG) | 636 (GG) | 0.26 | 0.90 | 0.75~1.08 | | Control | 22 (AA) | 257 (AG) | 624 (GG) | | rs4963 | Hypertensive | 192 (CC) | 432 (CG) | 278 (GG) | 0.02 | 0.85 | 0.75~0.97 | | Control | 224 (CC) | 441 (CG) | 239 (GG) | | rs3755885 | Hypertensive | 62 (CC) | 379 (CG) | 461 (GG) | 0.24 | 0.92 | 0.79~1.06 | | Control | 67 (CC) | 402 (CG) | 435 (GG) | | rs2071694 | Hypertensive | 447 (CC) | 374 (CG) | 82 (GG) | 0.81 | 0.98 | 0.85~1.13 | | Control | 455 (CC) | 366 (CG) | 83 (GG) | | rs3775067 | Hypertensive | 318 (AA) | 435 (AG) | 148 (GG) | 0.27 | 1.08 | 0.94~1.23 | | Control | 287 (AA) | 469 (AG) | 149 (GG) |
|
|
OR: odds ratio; CI: confidence interval.
|
