About this Journal Submit a Manuscript Table of Contents
BioMed Research International
Volume 2013 (2013), Article ID 454085, 6 pages
http://dx.doi.org/10.1155/2013/454085
Research Article

Increased Expression of TRPS1 Affects Tumor Progression and Correlates with Patients' Prognosis of Colon Cancer

1Department of General Surgery, Shanghai Putuo District Center Hospital, Shanghai 200062, China
2Department of General Surgery, Shanghai Zhabei District Shibei Hospital, Shanghai 200435, China
3Department of General Surgery, Shanghai Eighth People's Hospital, Shanghai 200235, China

Received 9 March 2013; Revised 8 May 2013; Accepted 9 May 2013

Academic Editor: Robert A. Vierkant

Copyright © 2013 Jun Hong et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Jemal, F. Bray, M. M. Center, J. Ferlay, E. Ward, and D. Forman, “Global cancer statistics,” CA: Cancer Journal for Clinicians, vol. 61, no. 2, pp. 69–90, 2011. View at Publisher · View at Google Scholar · View at Scopus
  2. C. J. A. Punt and J. Tol, “More is less-combining targeted therapies in metastatic colorectal cancer,” Nature Reviews Clinical Oncology, vol. 6, no. 12, pp. 731–733, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. Y. Hong, T. Downey, K. W. Eu, P. K. Koh, and P. Y. Cheah, “A “metastasis-prone” signature for early-stage mismatch-repair proficient sporadic colorectal cancer patients and its implications for possible therapeutics,” Clinical and Experimental Metastasis, vol. 27, no. 2, pp. 83–90, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. S. Zhou, D. Jin, and Y. Song, “Identification of a new mutation in TRPS1 gene leading to tricho-rhino-phalangeal syndrome I in a Chinese patient,” Journal of Dermatology, vol. 40, no. 4, pp. 277–278, 2013. View at Publisher · View at Google Scholar
  5. Y. B. Sohn, C. S. Ki, S. W. Park et al., “Clinical, biochemical, and genetic analysis of two korean patients with trichorhinophalangeal syndrome type I and growth hormone deficiency,” Annals of Clinical and Laboratory Science, vol. 42, pp. 307–312, 2012.
  6. A. Flores-Cuevas, O. Mutchinick, J. J. Morales-Suárez, L. M. González-Huerta, and S. A. Cuevas-Covarrubias, “Identification of two novel mutations in TRPS1 gene in families with tricho-rhino-phalangeal type I syndrome,” Journal of Investigative Medicine, vol. 60, pp. 823–826, 2012.
  7. I. Michikami, T. Fukushi, S. Honma et al., “Trps1 is necessary for normal temporomandibular joint development,” Cell and Tissue Research, vol. 348, no. 1, pp. 131–140, 2012. View at Publisher · View at Google Scholar
  8. N. Pereza, S. Severinski, S. Ostojić et al., “Third case of 8q23. 3-q24. 13 deletion in a patient with Langer-Giedion syndrome phenotype without TRPS1 gene deletion,” The American Journal of Medical Genetics A, vol. 158, no. 3, pp. 659–663, 2012. View at Publisher · View at Google Scholar
  9. G. T. G. Chang, G. J. C. M. van den Bemd, M. Jhamai, and A. O. Brinkmann, “Structure and function of GC79/TRPS1, a novel androgen-repressible apoptosis gene,” Apoptosis, vol. 7, no. 1, pp. 13–21, 2002. View at Publisher · View at Google Scholar · View at Scopus
  10. G. J. C. M. van den Bemd, M. Jhamai, A. O. Brinkmann, and G. T. G. Chang, “The atypical GATA protein TRPS1 represses androgen-induced prostate-specific antigen expression in LNCaP prostate cancer cells,” Biochemical and Biophysical Research Communications, vol. 312, no. 3, pp. 578–584, 2003. View at Publisher · View at Google Scholar · View at Scopus
  11. G. T. G. Chang, L. J. Blok, M. Steenbeek et al., “Differentially expressed genes in androgen-dependent and -independent prostate carcinomas,” Cancer Research, vol. 57, no. 18, pp. 4075–4081, 1997. View at Scopus
  12. N. A. Rahman, S. Kiiveri, S. Siltanen et al., “Adrenocortical tumorigenesis in transgenic mice: the role of luteinizing hormone receptor and transcription factors GATA-4 and GATA-61,” Reproductive Biology, vol. 1, no. 1, pp. 5–9, 2001.
  13. G. T. G. Chang, M. Steenbeek, E. Schippers et al., “Characterization of a zinc-finger protein and its association with apoptosis in prostate cancer cells,” Journal of the National Cancer Institute, vol. 92, no. 17, pp. 1414–1421, 2000. View at Scopus
  14. G. T. G. Chang, M. Jhamai, W. M. van Weerden, G. Jenster, and A. O. Brinkmann, “The TRPS1 transcription factor: androgenic regulation in prostate cancer and high expression in breast cancer,” Endocrine-Related Cancer, vol. 11, no. 4, pp. 815–822, 2004. View at Publisher · View at Google Scholar · View at Scopus
  15. G. T. G. Chang, S. C. Gamble, M. Jhamai, R. Wait, C. L. Bevan, and A. O. Brinkmann, “Proteomic analysis of proteins regulated by TRPS1 transcription factor in DU145 prostate cancer cells,” Biochimica et Biophysica Acta, vol. 1774, no. 5, pp. 575–582, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. S. Stinson, M. R. Lackner, A. T. Adai et al., “TRPS1 targeting by miR-221/222 promotes the epithelial-to-mesenchymal transition in breast cancer,” Science Signaling, vol. 4, no. 177, article ra41, 2011. View at Publisher · View at Google Scholar · View at Scopus