The Fc Receptor Polymorphisms and Expression of Neutrophil Activation Markers in Patients with Sickle Cell Disease from Western India

Table 5

Comparison of expression of CD32 with different genotypes of FcγRIIA and CD16 with different genotypes of FcγRIIIB.

	SCD-mild (90)			SCD-severe (61)
	H/H (18)	H/R (33)	R/R (39)	H/H (18)	H/R (23)	R/R (20)
	(Mean ± S.D.)	(Mean ± S.D.)	(Mean ± S.D.)	(Mean ± S.D.)	(Mean ± S.D.)	(Mean ± S.D.)
CD32 (MFI)	23.68±13.24	39.21±23.04	23.94±15.85	15.49±6.14	33.83±19.96	27.32±18.8
	NA1/NA2 (44)	NA2/NA2 (46)		NA1/NA2 (36)	NA2/NA2 (25)
CD16 (MFI)	171.33±85.08	162.22±69.42		177.59±88.61	206.48±92.60

Student’s 𝑡 test analysis comparing expression levels with different genotypes among mild versus severe SCD patients:
H/H: 𝑃-0.023; H/R: 𝑃-0.37; R/R: 𝑃-0.47.
NA1/NA2: 𝑃-0.75, NA2/NA2: 𝑃-0.03.