Table 2: Kinetic constants for the rate of formation and breakdown of the gem-diamine complex for mutant rcSHMT forms with glycine and L-serine substrates.

SubstratepHT253AT253C
 (s−1 M−1 · 104)   (s−1 M−1 · 106)   (s−1)   (s−1 M−1 · 104)
(s−1 M−1 · 106)

(s−1)

L-Serine

Glycine