Characterization of Schizophrenia Adverse Drug Interactions through a Network Approach and Drug Classification

Figure 1

Degree distributions and average degrees (vertical lines) of four drug sets. 𝑌-axis represents the proportion of drugs that have a degree while the 𝑋-axis is the drug degree. “SCZ-drugs” (red) denotes the 28 schizophrenia (SCZ) drugs. “other N-drugs” (blue) denotes the drugs belonging to the “nervous systems” category after exclusion of SCZ drugs. “non-N-drugs” (green) denotes the drugs not belonging to “nervous systems.” “all drugs in DDIs” (grey) denotes all drugs in the human DDIs. The inserted table summarizes the average degree for each drug set.