Characterization of Schizophrenia Adverse Drug Interactions through a Network Approach and Drug Classification

Table 1

Antipsychotics used to treat schizophrenia patients.

DrugBank ID	Drug name	Number of adverse drug interactions	Typical/atypical^a
DB01063	Acetophenazine	15	Typical
DB06288	Amisulpride	48	Atypical
DB01238	Aripiprazole	12	Atypical
DB00477	Chlorpromazine	51	Typical
DB01239	Chlorprothixene	4	Typical
DB00363	Clozapine	55	Atypical
DB00875	Flupenthixol	20	Typical
DB00623	Fluphenazine	28	Typical
DB00502	Haloperidol	58	Typical
DB00408	Loxapine	20	Typical
DB00933	Mesoridazine	74	Typical
DB01403	Methotrimeprazine	47	Typical
DB01618	Molindone	7	Atypical
DB00334	Olanzapine	10	Atypical
DB01267	Paliperidone	12	Atypical
DB00850	Perphenazine	31	Typical
DB01100	Pimozide	47	Typical
DB01621	Pipotiazine	6	Typical
DB00433	Prochlorperazine	29	Typical
DB01224	Quetiapine	29	Atypical
DB00734	Risperidone	27	Atypical
DB06144	Sertindole	2	Atypical
DB01622	Thioproperazine	3	Typical
DB00679	Thioridazine	86	Typical
DB01623	Thiothixene	96	Typical
DB00831	Trifluoperazine	30	Typical
DB00246	Ziprasidone	90	Atypical
DB01624	Zuclopenthixol	97	Typical

aAntipsychotic drugs are classified as typical and atypical mainly based on their different ability to cause extrapyramidal side effects (EPS).