Research Article

Effects of Tamarindus indica Fruit Pulp Extract on Abundance of HepG2 Cell Lysate Proteins and Their Possible Consequential Impact on Metabolism and Inflammation

Table 3

Top network and canonical pathways generated by Ingenuity Pathways Analysis.

Proteins subject
to analysis
Associated network
functions
ScorebTop canonical
pathway
value

Cell lysate
proteins
Hereditary disorder, metabolic disease, molecular transport48Mitochondrial Dysfunction
Cell lysate and secretory proteinsaLipid metabolism, molecular transport, small molecule Biochemistry31Gluconeogenesis I

aEarlier reported [7].
bA score of 2 or higher indicates at least a 99% confidence of not being generated by random chance and higher scores indicate a greater confidence.