Table 2: Genotype and allele distributions of −526, exon 4, exon 6, and 3UTR TOLLIP polymorphisms in LL and HS.

PolymorphismLL ( )
n (%)
HS ( )
n (%)
OR CI (95%) value

rs5743854
(−526 C>G)
Genotype
 C/C84 (86)127 (84)
 C/G13 (13)22 (14)0.89 (0.43–1.87)
 G/G1 (1)3 (2)0.50 (0.05–4.93)
Allele
 C181 (92)276 (91)
 G15 (8)28 (9)0.82 (0.42–0.16)
 HWE = 0.43
rs3750920
(1309956 C>T)
Genotype
 C/C24 (25)56 (37)
 C/T63 (64)83 (54)1.77 (0.99–3.16)
 T/T11 (11)13 (9)1.97 (0.772–5.02)
Allele
 C111 (57)195 (64)
 T85 (43)109 (36)1.37 (0.95–1.98)
HWE = 0.04
rs5744015
(1298430 C>A)
Genotype
 C/C96 (98)148 (97)
 C/A2 (2)4 (3)0.80 (0.14–4.29)
 A/A0 (0)0 (0)1.54 (0.03–78.2)
Allele
 C194 (99)300 (99)
 A 2 (1)4 (1)0.77 (0.14–4.26)
HWE = 1.00
rs3750919
(1292831 G>A)
Genotype
 G/G48 (49)81 (53)
 G/A40 (41)62 (41)1.09 (0.64–1.86)
 A/A10 (10)9 (6)1.87 (0.71–4.94)
Allele
 G136 (69)224 (74)
 A 60 (31) 80 (26)1.24 (0.83–1.84)
HWE = 0.81

LL: lepromatous leprosy; HS: healthy subjects; OR: odds ratio; C: confidence interval; HWE: Hardy-Weinberg equilibrium value; codominant model is presented.