Table 5: Results of community and residential studies measuring BMD.

Sample sizeRegimenMaximum followupSitesBMD change versus baseline (%)
ActiveComparatorP

Chapuy 56CaD versus P18 monthsFemoral neck
Total proximal femur
Trochanter
Intertrochanteric






0.036
<0.001
0.044
NS
Decalyos II 114CaD
versus P
2 yearsFemoral neck
Distal radius*
NS
583NANANS
Zhu 302CaD versus CaP1 yearTotal body
Total hip


NS
NS
Kyphos 120CaD versus P5 yearsTotal hip 0.05
Ooms 348D versus P2 yearsL femoral neck
R femoral neck
L femoral trochanter
R femoral trochanter
Distal radius
+1.6
+1.2
−1.1
−0.9
−2.7
−0.3
−1.4
−0.9
−0.9
−2.4
0.01
0.001
NS
NS
NS

Values are mean ± standard deviation; NS: not significant; CaD: calcium and vitamin D; P: placebo or control; NA: not available. *Single X-ray absorptiometry.