Research Article
Molecular Characterization and Clinical Impact of TMPRSS2-ERG Rearrangement on Prostate Cancer: Comparison between FISH and RT-PCR
Table 4
Correlation between the presence of TMPRSS2-ERG determined by FISH and/or RT-PCR and the CPP.
| | Parameters | TMPRSS2-ERG Negative (%) | TMPRSS2-ERG Positive (%) | |
| | PSA | | | | | <10 ng/mL | 85 (64.4) | 101 (62.3) | | | 10–20 ng/mL | 28 (21.2) | 38 (23.5) | 0.899 | | >20 ng/mL | 19 (14.4) | 23 (14.2) | | | Gleason-sp | | | | | 2–6 | 50 (37.9) | 68 (42) | | | 7 | 61 (46.2) | 78 (48.1) | 0.292 | | >7 | 21 (15.9) | 16 (9.9) | | | cT | | | | | ≤cT2b | 123 (93.2) | 150 (93.8) | 0.514 | | ≥cT3a | 9 (6.8) | 10 (6.3) | | pT | | | | | ≤pT2 | 74 (56.1) | 86 (53.4) | 0.369 | | ≥pT3 | 58 (43.9) | 75 (46.6) | | pN* | | | | | pN0 | 82 (96.5) | 108 (93.9) | 0.317 | | pN ≥ 1 | 3 (3.5) | 7 (6.1) | | Perineural invasion | | | | | Negative | 61 (51.7) | 65 (42.8) | 0.091 | | Positive | 57 (48.3) | 87 (53.3) |
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Lymphadenectomy was limited to the obturator fossa in most of the cases.
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