Table 3: Effects of paracetamol injury and A. blazei pretreatment on oxidative stress indicators in the liver and brain tissues. For experimental details see Section 2.

ParametersOrgan I, control II, A. blazei pretreatment III, paracetamol injury IV, A. blazei pretreatment + paracetamol injury

TBARS (nmol mg−1)Liver1.05 ± 0.19 ( )1.01 ± 0.18 ( )2.08 ± 0.23 ( )a,b,c1.08 ± 0.16 ( )
Brain2.64 ± 0.08 ( )2.73 ± 0.11 ( )3.29 ± 0.21 ( )a,b,c2.61 ± 0.18 ( )
ROS (nmol mg−1)Liver1.96 ± 0.38 ( )2.31 ± 0.28 ( )2.48 ± 0.48 ( )2.23 ± 0.47 ( )
Brain8.31 ± 0.91 ( )8.63 ± 0.66 ( )9.62 ± 0.69 ( )8.61 ± 0.74 ( )
GSH (nmol mg−1)Liver13.66 ± 0.65 ( )13.14 ± 0.71 ( )9.76 ± 0.91 ( )f,g12.66 ± 2.02 ( )
Brain8.82 ± 0.19 ( )8.79 ± 0.61 ( )7.31 ± 0.23 ( )h8.28 ± 0.45 ( )
Protein thiol groups (nmol mg−1)Liver115.3 ± 14.0 ( )122.6 ± 14.7 ( )80.7 ± 7.4 ( )101.1 ± 2.0 ( 4)
Brain95.2 ± 5.5 ( )95.0 ± 4.8 ( )84.4 ± 3.6 ( ) 84.4 ± 3.5 ( )

Significant differences ( ), according to one-way ANOVA followed by Student-Newman-Keuls post-hoc testing, are identified by the superscript letters as follows: aIII versus I; bIII versus II; cIII versus IV. Significant differences according to Student’s -test are given by the codes: f = 0.013 for III versus I; g = 0.026 for III versus I; h < 0.001 for III versus I.