Table 1: Release parameters ( ) of PenG sustained release and adjusted coefficient of determination ( ) values in various kinetic models tested.

Zero order First orderHiguchi   Korsmeyer Peppas
Cumulative release % versus time (day)log % drug remaining versus time (day)Cumulative % drug release versus square root of time (day)Baker-Lonsdalelog % cumulative versus log time (day)
n value

0.993.55 ± 0.070.830.12 ± 0.0120.9712.60 ± 0.390.9200.960.825.63 ± 0.71