Association between Inflammatory Marker, Environmental Lead Exposure, and Glutathione S-Transferase Gene

Table 3

The odds ratio (OR) for increasing inflammatory mark by genetic variations of GSTs in relation to blood lead level >6.47 𝜇g/dL.

GST genetic variation	CRP*
	OR	95% CI
GSTP1 (Ile105Val)
Ile/Ile	1	Reference
Ile/Val and Val/Val	1.46	1.05−2.20
GSTM1
+/+	1	Reference
−/−	1.32	1.03−1.69
GSTT1
+/+	1	Reference
−/−	1.65	1.17−2.35
GSTM1 and GSTT1
+/+	1	Reference
+/− or −/+	1.07	0.88−1.31
−/−	1.98	1.47−2.55

CRP: C-reactive protein; OR: odds ratio; CI: confidence interval.
*With adjustment for age, body mass index, smoking status, alcohol use, and blood pressure.