Research Article

Improvement of Daptomycin Production in Streptomyces roseosporus through the Acquisition of Pleuromutilin Resistance

Table 1

Bacterial strains used in this study.

Strains Description Reference

Streptomyces roseosporus ploxpWild-type strain containing a reporter plasmid in which pdptE was inserted in front of neo [13]
S.  roseosporus PLrplC G152V, Pler derivative of ploxpThis study
S.  roseosporus L2HrplC G152V, Pler derivative of ploxpThis study
S.  roseosporus PL11rplC G152V, Pler derivative of ploxpThis study
S.  roseosporus LDRPler derivative of ploxp with unknown mutation siteThis study
S.  roseosporus M234Pler derivative of ploxp with unknown mutation siteThis study
Micrococcus  luteus Daptomycin-sensitive indicator strain[13]