Figure 4: Effects of sesamol on mucosal pro-inflammatory cytokines production in water immersion restraint- (WIR-) treated rats. Rats were divided into five groups of five: Group I, non-WIR (normal) group; Group II, WIR (control) group rats were subjected to WIR; and Groups III–V, sesamol-plus-WIR group rats were orally given sesamol (0.1, 0.3, and 1 mg/kg, resp.) 30 min before WIR. Mucosal TNF-α (a), IL-1β (b), and IL-6 (c) levels were measured after WIR. Data are means ± standard deviation (SD). Significant differences between measurement traits were analyzed using one-way ANOVA. Different letters between groups indicate statistically significant differences ().