Immunogenic Cell Death: Can It Be Exploited in PhotoDynamic Therapy for Cancer?

Figure 2

Molecular mechanisms of PDT-induced Immunogenic Cell Death (ICD). The three main processes characterizing the ICD are the preapoptotic cell surface exposure of calreticulin (CRT) and HSP70, the secretion of ATP and HSP70, and the postapoptotic release of HMGB1 and HSP70.