Table 4: Genotype and allele frequency distribution of NRAMP1 and VDR genes in the controls and TB patients of the Chinese Kazak population.

Genotype and alleleTuberculosis
(Freq)
Control 
 (Freq)
OR (95% CI)

NRAMP1-3′UTR
 TGTG++138 (64.8)167 (79.1)1.00
 TGTG+/del63 (29.6)41 (19.5)12.8021.859 (1.182–2.926)0.002
 TGTGdel/del12 (5.6)3 (1.4)4.841 (1.339–17.499)
Alleles
 TGTG339 (79.6)375 (88.9)13.7372.048 (1.395–3.006) <0.001
 TGTGdel87 (20.4) 47 (11.1)
VDR-FokI
 FF72 (33.8)101 (47.9)1.00
 Ff96 (45.1)88 (41.7)13.0951.530 (1.007–2.325)0.001
 ff45 (21.1)22 (10.4)2.869 (1.586–5.191)
Alleles
 F240 (56.3)290 (68.7)13.8681.703 (1.285–2.255) <0.001
 f186 (43.7) 132 (31.3)
VDR-TaqI
 TT191 (89.7)183 (86.7)1.00
 Tt19 (8.9)23 (10.9)0.791 (0.417–1.502)0.581
 tt3 (1.4)5 (2.4)0.575 (0.135–2.440)
Alleles
 T401 (94.1)389 (92.2)1.2670.735 (0.429–1.259)0.260
 t25 (5.9)33 (7.8)

Note: Genotype frequencies were compared between the patients and control subjects by test or Fisher’s exact test when appropriate. Allele frequencies were compared between the patients and control subjects by use of a test for 2-by-2 contingency tables. : the sample size; OR: odds ratio; 95% CI: 95% confidence interval; Freq: frequency.