High Insulin and Leptin Increase Resistin and Inflammatory Cytokine Production from Human Mononuclear Cells

Table 1

Anthropometic and biochemical characteristics and plasma resistin, TNF-α, IL-6, and adiponectin levels of the 10 healthy volunteers as a whole, and further divided in women and men.

	Total subjects (𝑛=10)	Women (𝑛=5)	Men (𝑛=5)	𝑃 value
Age (years)	34.7±1.17	32.8±1.31	36.6±1.6	0.056
BMI (Kg/m^2)	25.7±1.19	24.48±2.28	26.83±0.69	0.151
Fasting insulin (μU/mL)	10.8±1.3	10.38±1.81	11.23±2.07	0.841
Fasting glucose (mg/dL)	79.4±3.67	81.96±7.3	76.84±1.97	0.222
HOMA-IR index	2.16±0.32	2.17±0.54	2.15±0.41	0.690
FFA (mM)	0.22±0.05	0.28±0.09	0.14±0.04	0.190
CRP (mg/L)	0.38±0.15	0.31±0.16	0.46±0.31	0.905
Resistin (ng/mL)	6.27±0.49	6.85±0.77	5.55±0.36	0.190
TN-α (pg/mL)	1.46±0.37	1.19±0.29	1.73±0.69	0.841
IL-6 (pg/mL)	7.3±3.90	1.69±0.19	12.90±5.32	0.333
Adiponectin (μg/mL)	20.99±4.7	30.72±6.32	11.26±3.49	0.016

BMI: Body Mass Index; HOMA-IR: homeostasis model assessment; FFA: free fatty acids; CRP: C-reactive protein. Data were expressed as means ± SEM. 𝑃 value gives the statistical difference between women and men.