High Insulin and Leptin Increase Resistin and Inflammatory Cytokine Production from Human Mononuclear Cells
Table 2
Bivariate correlations of secreted resistin, TNF-α, IL-6, and IL-1β protein with their corresponding basal mRNA levels and the studied metabolic parameters.
Secreted resistin (ng/mL)
Secreted TNF-α (pg/mL)
Secreted IL-6 (pg/mL)
Secreted IL-1β (pg/mL)
Secreted TNF-α (pg/mL)
−0.167
Secreted IL-6 (pg/mL)
−0.600
0.491
Secreted IL-1β (pg/mL)
0.048
0.733
*
0.017
Relative resistin mRNA levels
0.083
−0.224
−0.321
0.167
Relative TNF-α mRNA levels
0.143
0.667
**
0.033
0.833
*
Relative IL-6 mRNA levels
−0.071
−0.357
0.286
0.690
Relative IL-1β mRNA levels
0.071
0.381
0.429
0.036
BMI (Kg/m2)
−0.017
−0.127
0.042
−0.433
Fasting insulin (μU/mL)
−0.317
−0.127
0.176
−0.417
Fasting glucose (mg/dL)
0.450
−0.552
−0.018
−0.517
FFA (mM)
−0.108
−0.017
0.487
−0.143
CRP (mg/L)
−0.514
−0.479
0.297
−0.730
*
BMI: Body Mass Index; FFA: free fatty acids. CRP: C-reactive protein. Numbers represent values. *, **.
