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BioMed Research International
Volume 2013 (2013), Article ID 493643, 10 pages
Mood and Memory Function in Ovariectomised Rats Exposed to Social Instability Stress
1Department of Physiology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
2Department of Psychiatry, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
3Department of Anatomy, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
4Department of Neuroscience, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
5Department of Community Medicine, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
Received 4 April 2013; Accepted 25 May 2013
Academic Editor: Shahrzad Bazargan-Hejazi
Copyright © 2013 Badriya Al-Rahbi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- M. M. Weissman, R. Bland, P. R. Joyce, S. Newman, J. E. Wells, and H.-U. Wittchen, “Sex differences in rates of depression: cross-national perspectives,” Journal of Affective Disorders, vol. 29, no. 2-3, pp. 77–84, 1993.
- H. D. Desai and M. W. Jann, “Major depression in women: a review of the literature,” Journal of the American Pharmaceutical Association, vol. 40, no. 4, pp. 525–537, 2000.
- P. P. Zandi, M. C. Carlson, B. L. Plassman et al., “Hormone replacement therapy and incidence of Alzheimer disease in older women. The Cache County Study,” Journal of the American Medical Association, vol. 288, no. 17, pp. 2123–2129, 2002.
- R. C. Kessler, P. Berglund, O. Demler et al., “The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R),” Journal of the American Medical Association, vol. 289, no. 23, pp. 3095–3105, 2003.
- C. Dalla, K. Antoniou, G. Drossopoulou et al., “Chronic mild stress impact: are females more vulnerable?” Neuroscience, vol. 135, no. 3, pp. 703–714, 2005.
- S. L. Baker, A. C. Kentner, A. T. M. Konkle, L. Santa-Maria Barbagallo, and C. Bielajew, “Behavioral and physiological effects of chronic mild stress in female rats,” Physiology and Behavior, vol. 87, no. 2, pp. 314–322, 2006.
- A. L. Morrow, “Recent developments in the significance and therapeutic relevance of neuroactive steroids—introduction to the special issue,” Pharmacology and Therapeutics, vol. 116, no. 1, pp. 1–6, 2007.
- B. B. Sherwin and J. F. Henry, “Brain aging modulates the neuroprotective effects of estrogen on selective aspects of cognition in women: a critical review,” Frontiers in Neuroendocrinology, vol. 29, no. 1, pp. 88–113, 2008.
- N. F. Woods, E. S. Mitchell, and C. Adams, “Memory functioning among midlife women: observations from the Seattle Midlife Women's Health Study,” Menopause, vol. 7, no. 4, pp. 257–265, 2000.
- P. J. Schmidt, N. Haq, and D. R. Rubinow, “A longitudinal evaluation of the relationship between reproductive status and mood in perimenopausal women,” American Journal of Psychiatry, vol. 161, no. 12, pp. 2238–2244, 2004.
- P. J. Schmidt and D. R. Rubinow, “Menopause-related affective disorders: a justification for further study,” American Journal of Psychiatry, vol. 148, no. 7, pp. 844–852, 1991.
- A. J. Romanoski, M. F. Folstein, G. Nestadt et al., “The epidemiology of psychiatrist-ascertained depression and DSM-III depressive disorders. Results from the eastern Baltimore mental health survey clinical reappraisal,” Psychological Medicine, vol. 22, no. 3, pp. 629–655, 1992.
- M. Pokorski and P. Siwiec, “Memory, depression, and progressing old age in women,” Journal of Physiology and Pharmacology, vol. 57, no. 4, pp. 297–304, 2006.
- R. B. Gibbs and P. Aggarwal, “Estrogen and basal forebrain cholinergic neurons: implications for brain aging and Alzheimer's disease-related cognitive decline,” Hormones and Behavior, vol. 34, no. 2, pp. 98–111, 1998.
- V. N. Luine, S. T. Richards, V. Y. Wu, and K. D. Beck, “Estradiol enhances learning and memory in a spatial memory task and effects levels of monoaminergic neurotransmitters,” Hormones and Behavior, vol. 34, no. 2, pp. 149–162, 1998.
- R. Rupprecht, “Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties,” Psychoneuroendocrinology, vol. 28, no. 2, pp. 139–168, 2003.
- A. A. Walf and C. A. Frye, “A review and update of mechanisms of estrogen in the hippocampus and amygdala for anxiety and depression behavior,” Neuropsychopharmacology, vol. 31, no. 6, pp. 1097–1111, 2006.
- C. A. Frye, A. A. Walf, M. E. Rhodes, and J. P. Harney, “Progesterone enhances motor, anxiolytic, analgesic, and antidepressive behavior of wild-type mice, but not those deficient in type 1 5α-reductase,” Brain Research, vol. 1004, no. 1-2, pp. 116–124, 2004.
- W. A. Koss, D. R. Gehlert, and A. Shekhar, “Different effects of subchronic doses of 17-β estradiol in two ethologically based models of anxiety utilizing female rats,” Hormones and Behavior, vol. 46, no. 2, pp. 158–164, 2004.
- A. A. Walf and C. A. Frye, “ERβ-selective estrogen receptor modulators produce antianxiety behavior when administered systemically to ovariectomized rats,” Neuropsychopharmacology, vol. 30, no. 9, pp. 1598–1609, 2005.
- P. R. Rapp, J. H. Morrison, and J. A. Roberts, “Cyclic estrogen replacement improves cognitive function in aged ovariectomized rhesus monkeys,” Journal of Neuroscience, vol. 23, no. 13, pp. 5708–5714, 2003.
- B. Leuner, S. Mendolia-Loffredo, and T. J. Shors, “High levels of estrogen enhance associative memory formation in ovariectomized females,” Psychoneuroendocrinology, vol. 29, no. 7, pp. 883–890, 2004.
- L. Martínez-Mota, C. M. Contreras, and M. Saavedra, “Progesterone reduces immobility in rats forced to swim,” Archives of Medical Research, vol. 30, no. 4, pp. 286–289, 1999.
- I. M. Rachman, J. R. Unnerstall, D. W. Pfaff, and R. S. Cohen, “Estrogen alters behavior and forebrain c-fos expression in ovariectomized rats subjected to the forced swim test,” Proceedings of the National Academy of Sciences of the United States of America, vol. 95, no. 23, pp. 13941–13946, 1998.
- B. A. Rocha, R. Fleischer, J. M. Schaeffer, S. P. Rohrer, and G. J. Hickey, “17β-Estradiol-induced antidepressant-like effect in the Forced Swim Test is absent in estrogen receptor-β knockout (BERKO) mice,” Psychopharmacology, vol. 179, no. 3, pp. 637–643, 2005.
- E. Estrada-Camarena, A. Fernández-Guasti, and C. López-Rubalcava, “Antidepressant-like effect of different estrogenic compounds in the forced swimming test,” Neuropsychopharmacology, vol. 28, no. 5, pp. 830–838, 2003.
- C. A. Frye and J. Wawrzycki, “Effect of prenatal stress and gonadal hormone condition on depressive behaviors of female and male rats,” Hormones and Behavior, vol. 44, no. 4, pp. 319–326, 2003.
- C. A. Frye and A. A. Walf, “Estrogen and/or progesterone administered systemically or to the amygdala can have anxiety-, fear-, and pain-reducing effects in ovariectomized rats,” Behavioral Neuroscience, vol. 118, no. 2, pp. 306–313, 2004.
- A. A. Walf and C. A. Frye, “The use of the elevated plus maze as an assay of anxiety-related behavior in rodents,” Nature Protocols, vol. 2, no. 2, pp. 322–328, 2007.
- A. A. Walf, M. E. Rhodes, and C. A. Frye, “Ovarian steroids enhance object recognition in naturally cycling and ovariectomized, hormone-primed rats,” Neurobiology of Learning and Memory, vol. 86, no. 1, pp. 35–46, 2006.
- K. T. Brady, T. K. Killeen, T. Brewerton, and S. Lucerini, “Comorbidity of psychiatric disorders and posttraumatic stress disorder,” Journal of Clinical Psychiatry, vol. 61, no. 7, pp. 22–32, 2000.
- N. Breslau, “Epidemiologic studies of trauma, posttraumatic stress disorder, and other psychiatric disorders,” Canadian Journal of Psychiatry, vol. 47, no. 10, pp. 923–929, 2002.
- B. S. McEwen, “Protection and damage from acute and chronic stress: allostasis and allostatic overload and relevance to the pathophysiology of psychiatric disorders,” Annals of the New York Academy of Sciences, vol. 1032, pp. 1–7, 2004.
- M. Sala, J. Perez, P. Soloff et al., “Stress and hippocampal abnormalities in psychiatric disorders,” European Neuropsychopharmacology, vol. 14, no. 5, pp. 393–405, 2004.
- K.-S. Kim and P.-L. Han, “Optimization of chronic stress paradigms using anxiety- and depression-like behavioral parameters,” Journal of Neuroscience Research, vol. 83, no. 3, pp. 497–507, 2006.
- E. Y. Sterner and L. E. Kalynchuk, “Behavioral and neurobiological consequences of prolonged glucocorticoid exposure in rats: relevance to depression,” Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 34, no. 5, pp. 777–790, 2010.
- P. T. Loosen, “Cushing's syndrome and depression,” Endocrinologist, vol. 4, no. 5, pp. 373–382, 1994.
- B. S. McEwen, “Allostasis and allostatic load: implications for neuropsychopharmacology,” Neuropsychopharmacology, vol. 22, no. 2, pp. 108–124, 2000.
- R. M. Sapolsky, “Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders,” Archives of General Psychiatry, vol. 57, no. 10, pp. 925–935, 2000.
- J. Herbert, “Stress, the brain, and mental illness,” British Medical Journal, vol. 315, no. 7107, pp. 530–535, 1997.
- J. P. ter Horst, E. R. de Kloet, H. Schächinger, and M. S. Oitzl, “Relevance of stress and female sex hormones for emotion and cognition,” Cellular and Molecular Neurobiology, vol. 32, no. 5, pp. 725–735, 2012.
- R. L. Butcher, W. E. Collins, and N. W. Fugo, “Plasma concentration of LH, FSH, prolactin, progesterone and estradiol-17beta throughout the 4-day estrous cycle of the rat,” Endocrinology, vol. 94, no. 6, pp. 1704–1708, 1974.
- H. Liang, S. Pun, and T. J. Wronski, “Bone anabolic effects of basic fibroblast growth factor in ovariectomized rats,” Endocrinology, vol. 140, no. 12, pp. 5780–5788, 1999.
- B. G. Saruhan and M. A. Ketani, “Effects of ovariectomy and estrogen replacement on rat tongue mucosa,” Inönü Üniversitesi Tip Fakültesi Dergisi, vol. 13, pp. 141–145, 2006.
- H.-Y. Liu, A. T. H. Wu, C.-Y. Tsai et al., “The balance between adipogenesis and osteogenesis in bone regeneration by platelet-rich plasma for age-related osteoporosis,” Biomaterials, vol. 32, no. 28, pp. 6773–6780, 2011.
- D. Sandoval, K. Ryan, A. De Kloet, S. Woods, and R. Seeley, “Female rats are relatively more sensitive to reduced lipid versus reduced carbohydrate availability,” Nutrition & Diabetes, vol. 2, article e27, 2012.
- J. Haller and J. Halász, “Mild social stress abolishes the effects of isolation on anxiety and chlordiazepoxide reactivity,” Psychopharmacology, vol. 144, no. 4, pp. 311–315, 1999.
- M. J. Detke and I. Lucki, “Detection of serotonergic and noradrenergic antidepressants in the rat forced swimming test: the effects of water depth,” Behavioural Brain Research, vol. 73, no. 1-2, pp. 43–46, 1995.
- M. J. Detke, M. Rickels, and I. Lucki, “Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants,” Psychopharmacology, vol. 121, no. 1, pp. 66–72, 1995.
- M. J. Detke, S. Wieland, and I. Lucki, “Blockade of the antidepressant-like effects of 8-OH-DPAT, buspirone and desipramine in the rat forced swim test by 5HT(1A) receptor antagonists,” Psychopharmacology, vol. 119, no. 1, pp. 47–54, 1995.
- M. N. M. De Lima, D. C. Laranja, E. Bromberg, R. Roesler, and N. Schröder, “Pre- or post-training administration of the NMDA receptor blocker MK-801 impairs object recognition memory in rats,” Behavioural Brain Research, vol. 156, no. 1, pp. 139–143, 2005.
- C. Pietá Dias, M. N. Martins de Lima, J. Presti-Torres et al., “Memantine reduces oxidative damage and enhances long-term recognition memory in aged rats,” Neuroscience, vol. 146, no. 4, pp. 1719–1725, 2007.
- R. E. Bowman, D. Ferguson, and V. N. Luine, “Effects of chronic restraint stress and estradiol on open field activity, spatial memory, and monoaminergic neurotransmitters in ovariectomized rats,” Neuroscience, vol. 113, no. 2, pp. 401–410, 2002.
- O. A. H. Reneerkens, K. Rutten, S. Akkerman et al., “Phosphodiesterase type 5 (PDE5) inhibition improves object recognition memory: indications for central and peripheral mechanisms,” Neurobiology of Learning and Memory, vol. 97, no. 4, pp. 370–379, 2012.
- H. Kamei, T. Nagai, H. Nakano et al., “Repeated methamphetamine treatment impairs recognition memory through a failure of novelty-induced ERK1/2 activation in the prefrontal cortex of mice,” Biological Psychiatry, vol. 59, no. 1, pp. 75–84, 2006.
- V. P. Carlini, A. C. Martini, H. B. Schiöth, R. D. Ruiz, M. Fiol de Cuneo, and S. R. de Barioglio, “Decreased memory for novel object recognition in chronically food-restricted mice is reversed by acute ghrelin administration,” Neuroscience, vol. 153, no. 4, pp. 929–934, 2008.
- L. A. Brotto, A. M. Barr, and B. B. Gorzalka, “Sex differences in forced-swim and open-field test behaviours after chronic administration of melatonin,” European Journal of Pharmacology, vol. 402, no. 1-2, pp. 87–93, 2000.
- R. D. Porsolt, G. Anton, N. Blavet, and M. Jalfre, “Behavioural despair in rats: a new model sensitive to antidepressant treatments,” European Journal of Pharmacology, vol. 47, no. 4, pp. 379–391, 1978.
- J.-P. Rénéric, M. Bouvard, and L. Stinus, “Idazoxan and 8-OH-DPAT modify the behavioral effects induced by either NA, or 5-HT, or dual NA/5-HT reuptake inhibition in the rat forced swimming test,” Neuropsychopharmacology, vol. 24, no. 4, pp. 379–390, 2001.
- R. L. Goodman, “A quantitative analysis of the physiological role of estradiol and progesterone in the control of tonic and surge secretion of luteinizing hormone in the rat,” Endocrinology, vol. 102, no. 1, pp. 142–150, 1978.
- S. D. Bain, M. C. Bailey, D. L. Celino, M. M. Lantry, and M. W. Edwards, “High-dose estrogen inhibits bone resorption and stimulates bone formation in the ovariectomized mouse,” Journal of Bone and Mineral Research, vol. 8, no. 4, pp. 435–442, 1993.
- S. Mora, N. Dussaubat, and G. Díaz-Véliz, “Effects of the estrous cycle and ovarian hormones on behavioral indices of anxiety in female rats,” Psychoneuroendocrinology, vol. 21, no. 7, pp. 609–620, 1996.
- A. A. Walf, J. J. Paris, and C. A. Frye, “Chronic estradiol replacement to aged female rats reduces anxiety-like and depression-like behavior and enhances cognitive performance,” Psychoneuroendocrinology, vol. 34, no. 6, pp. 909–916, 2009.
- M. Okada, N. Hayashi, M. Kometani, K. Nakao, and T. Inukai, “Influences of ovariectomy and continuous replacement of 17β-estradiol on the tail skin temperature and behavior in the forced swimming test in rats,” Japanese Journal of Pharmacology, vol. 73, no. 1, pp. 93–96, 1997.
- A. Biegon, A. Reches, L. Snyder, and B. S. McEwen, “Serotonergic and noradrenergic receptors in the rat brain: modulation by chronic exposure to ovarian hormones,” Life Sciences, vol. 32, no. 17, pp. 2015–2021, 1983.
- T. Kobayashi, T. Kobayashi, J. Kato, and H. Minaguchi, “Cholinergic and adrenergic mechanisms in the female rat. Hypothalamus with special reference to feedback of ovarian steroid hormones,” Steroid Dynamics, vol. 296, pp. 303–339, 1966.
- C. J. Herzog, B. Czéh, S. Corbach et al., “Chronic social instability stress in female rats: a potential animal model for female depression,” Neuroscience, vol. 159, no. 3, pp. 982–992, 2009.
- M. D. Braquehais, M. D. Picouto, M. Casas, and L. Sher, “Hypothalamic-pituitary-adrenal axis dysfunction as a neurobiological correlate of emotion dysregulation in adolescent suicide,” World Journal of Pediatrics, vol. 8, no. 3, pp. 197–206, 2012.
- D. J. Nutt and A. L. Malizia, “Structural and functional brain changes in posttraumatic stress disorder,” Journal of Clinical Psychiatry, vol. 65, no. 1, pp. 11–17, 2004.
- D. R. Lara and H. S. Akiskal, “Toward an integrative model of the spectrum of mood, behavioral and personality disorders based on fear and anger traits—II. Implications for neurobiology, genetics and psychopharmacological treatment,” Journal of Affective Disorders, vol. 94, no. 1–3, pp. 89–103, 2006.
- C. M. McCormick and I. Z. Mathews, “Adolescent development, hypothalamic-pituitary-adrenal function, and programming of adult learning and memory,” Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 34, no. 5, pp. 756–765, 2010.
- A. McGirr, G. Diaconu, M. T. Berlim et al., “Dysregulation of the sympathetic nervous system, hypothalamic-pituitary-adrenal axis and executive function in individuals at risk for suicide,” Journal of Psychiatry and Neuroscience, vol. 35, no. 6, pp. 399–408, 2010.
- B. S. McEwen, “Plasticity of the hippocampus: adaptation to chronic stress and allostatic load,” Annals of the New York Academy of Sciences, vol. 933, pp. 265–277, 2001.
- R. M. Sapolsky, “Glucocorticoids, stress, and their adverse neurological effects: relevance to aging,” Experimental Gerontology, vol. 34, no. 6, pp. 721–732, 1999.
- B. Roozendaal, C. L. Williams, and J. L. McGaugh, “Glucocorticoid receptor activation in the rat nucleus of the solitary tract facilitates memory consolidation: involvement of the basolateral amygdala,” European Journal of Neuroscience, vol. 11, no. 4, pp. 1317–1323, 1999.
- J. V. Seale, S. A. Wood, H. C. Atkinson, M. S. Harbuz, and S. L. Lightman, “Gonadal steroid replacement reverses gonadectomy-induced changes in the corticosterone pulse profile and stress-induced hypothalamic-pituitary-adrenal axis activity of male and female rats,” Journal of Neuroendocrinology, vol. 16, no. 12, pp. 989–998, 2004.
- M. P. Carey, C. H. Deterd, J. De Koning, F. Helmerhorst, and E. R. De Kloet, “The influence of ovarian steroids on hypothalamic-pituitary-adrenal regulation in the female rat,” Journal of Endocrinology, vol. 144, no. 2, pp. 311–321, 1995.
- J. Zhang, M. Inazu, K. Tsuji, E. Yamada, H. Takeda, and T. Matsumiya, “Neurochemical characteristics and behavioral responses to psychological stress in ovariectomized rats,” Pharmacological Research, vol. 39, no. 6, pp. 455–461, 1999.