Liposomes-in-Hydrogel Delivery System with Mupirocin: In Vitro Antibiofilm Studies and In Vivo Evaluation in Mice Burn Model
Figure 3
Histological photographs of burn wounds, 28 days after induction. Sections are stained with hematoxylin and eosin. Scale bars: 1 mm. Representative samples are shown from animals treated with (a) Bactroban, Group I; (b) mupirocin-in-liposomes, Group II; (c) plain chitosan hydrogel, Group III; and (d) mupirocin-in-liposomes-in-hydrogel, Group IV. (e) shows a healed burn wound from a nontreated mouse (Group V, control). Arrows point to epidermis, and (*) indicates dermis in (a)–(e). Arrow heads in (b) and (c) point to the keratin layer which often detached during tissue preparation.
