Association of Atherosclerotic Peripheral Arterial Disease with Adiponectin Genes SNP+45 and SNP+276: A Case-Control Study
Table 1
Anthropometric and biochemical characteristics by groups.
Variable
PAD group
Non-PAD group
Comparison between groups P-value
Gender: male*,a
82
80
0.603
Smokers*,a
62
43
<0.001
DM*,a
33
32
0.840
Obesity*,a
20
22
0.665
AHT*,a
61
48
0.024
Antihypertensive agentsa
53
42
0.049
CAD*,a
53
37
0.005
Age (years)**,b
63 (56; 74)
62 (57; 71)
0.626
BMI (kg/m2)**,b
25.82 (23.12; 29.07)
25.73 (22.71; 29.34)
0.896
Cholesterol (mg/dL)**,b
194 (167; 230)
191 (157; 223)
0.139
TG (mg/dL)**,b
113 (89; 140)
104 (80; 139)
0.028
HDL (mg/dL)**,b
49 (42; 56)
48 (41; 55)
0.356
Statinsa
75
72
0.549
Glycemia (mg/dL)**,b
96 (86; 126)
96 (86; 108)
0.207
Diabetes durationa
≤5 years
7
8
0.739
5–10 years
13
13
>0.999
>10 years
12
9
0.376
Diabetes treatmenta
Oral hypoglycemic agent***
8
10
0.542
Insulin therapy
17
17
>0.999
Oral and Insulin therapy
7
4
0.224
Creatinine (mg/dL)**,b
0.90 (0.70; 1.00)
0.90 (0.70; 1.00)
0.094
Fibrinogen (mg/dL)**,b
306 (249; 367)
343 (310; 387)
<0.001c
CRP (mg/dL)**,b
0.70 (0.50; 0.90)
0.90 (0.60; 1.00)
0.816
% [95% CI]; **median (Q1; Q3), where Q1 = 25th percentile; Q3 = 75th percentile; ***biguanides or sulfonylurea; aP value associated with -test; bP-value associated with Mann-Whitney test; cnormal limits for both groups; DM: diabetes mellitus; AHT: arterial hypertension; CAD: coronary artery disease; BMI: body mass index; TG: triglycerides; HDL: high density lipoprotein; CRP: C-reactive protein.