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BioMed Research International
Volume 2013 (2013), Article ID 503419, 5 pages
Endometrial Polyps in Women Affected by Levothyroxine-Treated Hypothyroidism—Histological Features, Immunohistochemical Findings, and Possible Explanation of Etiopathogenic Mechanism: A Pilot Study
1Department of Women’s and Children’s Health, University of Padua, 35128 Padua, Italy
2Department of Medical Diagnostic and Special Therapy, University of Padua, 35128 Padua, Italy
3Ospedale San Bassiano, OB/GYN Unit, 36061 Bassano del Grappa, Vicenza, Italy
Received 29 April 2013; Accepted 19 July 2013
Academic Editor: Kyousuke Takeuchi
Copyright © 2013 Carlo Saccardi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- S. Salim, H. Won, E. Nesbitt-Hawes, N. Campbell, and J. Abbott, “Diagnosis and management of endometrial polyps: a critical review of the literature,” Journal of Minimally Invasive Gynecology, vol. 18, no. 5, pp. 569–581, 2011.
- R. Haimov-Kochman, R. Deri-Hasid, Y. Hamani, and E. Voss, “The natural course of endometrial polyps: could they vanish when left untreated?” Fertility and Sterility, vol. 92, no. 2, pp. 828.e11–828.e12, 2009.
- E. Dreisler, S. Stampe Sorensen, P. H. Ibsen, and G. Lose, “Prevalence of endometrial polyps and abnormal uterine bleeding in a Danish population aged 20–74 years,” Ultrasound in Obstetrics and Gynecology, vol. 33, no. 1, pp. 102–108, 2009.
- P. Litta, E. Cosmi, C. Saccardi, C. Esposito, R. Rui, and G. Ambrosini, “Outpatient operative polypectomy using a 5 mm-hysteroscope without anaesthesia and/or analgesia: advantages and limits,” European Journal of Obstetrics Gynecology and Reproductive Biology, vol. 139, no. 2, pp. 210–214, 2008.
- L. Nappi, U. Indraccolo, A. di Spiezio Sardo et al., “Are diabetes, hypertension, and obesity independent risk factors for endometrial polyps?” Journal of Minimally Invasive Gynecology, vol. 16, no. 2, pp. 157–162, 2009.
- P. McGurgan, L. J. Taylor, S. R. Duffy, and P. J. O'Donovan, “Are endometrial polyps from pre-menopausal women similar to post-menopausal women? An immunohistochemical comparison of endometrial polyps from pre- and post-menopausal women,” Maturitas, vol. 54, no. 3, pp. 277–284, 2006.
- H. Maia, A. Maltez, C. Athayde, and E. M. Coutinho, “Proliferation profile of endometrial polyps in post-menopausal women,” Maturitas, vol. 40, no. 3, pp. 273–281, 2001.
- K. Mittal, L. Schwartz, S. Goswami, and R. Demopoulos, “Estrogen and progesterone receptor expression in endometrial polyps,” International Journal of Gynecological Pathology, vol. 15, no. 4, pp. 345–348, 1996.
- H. Maia Jr., A. Maltez, L. C. Calmon, M. Oliveira, D. Marques, and E. M. Coutinho, “Histopathology and steroid receptors in endometrial polyps of postmenopausal patients under hormone-replacement therapy,” Gynaecological Endoscopy, vol. 7, no. 5, pp. 267–272, 1998.
- L. J. Taylor, T. L. Jackson, J. G. Reid, and S. R. G. Duffy, “The differential expression of oestrogen receptors, progesterone receptors, Bcl-2 and Ki67 in endometrial polyps,” BJOG, vol. 110, no. 9, pp. 794–798, 2003.
- B. Scoccia, H. Demir, Y. Kang, M. A. Fierro, and N. J. Winston, “In vitro fertilization pregnancy rates in levothyroxine-treated women with hypothyroidism compared to women without thyroid dysfunction disorders,” Thyroid, vol. 22, no. 6, pp. 631–636, 2012.
- L. Aghajanova, A. Stavreus-Evers, M. Lindeberg, B.-M. Landgren, L. S. Sparre, and O. Hovatta, “Thyroid-stimulating hormone receptor and thyroid hormone receptors are involved in human endometrial physiology,” Fertility and Sterility, vol. 95, no. 1, pp. 230–237, 2011.
- R. D. Catalano, H. O. Critchley, O. Heikinheimo et al., “Mifepristone induced progesterone withdrawal reveals novel regulatory pathways in human endometrium,” Molecular Human Reproduction, vol. 13, no. 9, pp. 641–654, 2007.
- E. C. Sant'Ana de Almeida, A. A. Nogueira, F. J. Candido dos Reis, L. N. Zambelli Ramalho, and S. Zucoloto, “Immunohistochemical expression of estrogen and progesterone receptors in endometrial polyps and adjacent endometrium in postmenopausal women,” Maturitas, vol. 49, no. 3, pp. 229–233, 2004.
- Z. Liu, S. Kuokkanen, and L. Pal, “Steroid hormone receptor profile of premenopausal endometrial polyps,” Reproductive Sciences, vol. 17, no. 4, pp. 377–383, 2010.
- N. Fujimoto, N. Jinno, and S. Kitamura, “Activation of estrogen response element dependent transcription by thyroid hormone with increase in estrogen receptor levels in a rat pituitary cell line, GH3,” Journal of Endocrinology, vol. 181, no. 1, pp. 77–83, 2004.
- S. Dinda, A. Sanchez, and V. Moudgil, “Estrogen-like effects of thyroid hormone on the regulation of tumor suppressor proteins, p53 and retinoblastoma, in breast cancer cells,” Oncogene, vol. 21, no. 5, pp. 761–768, 2002.