Endometrial Polyps in Women Affected by Levothyroxine-Treated Hypothyroidism—Histological Features, Immunohistochemical Findings, and Possible Explanation of Etiopathogenic Mechanism: A Pilot Study

Table 2

Immunohistochemical endometrial polyps features: Group A (treatment) versus Group B (controls).

Group	Total number	Stromal ERs intensity	Number (%)	𝑃	Glandular ERs intensity	Number (%)	𝑃
A	12	Low	2 (16.7)		Low	2 (16.7)	0.05
		High	10 (83.3)	0.02	High	10 (83.3)
B	10	Low	9 (90)		Low	4 (40)
		High	1 (10)		High	6 (60)
Group	Total number	Percentage of stromal ERs	Number (%)	𝑃	Percentage of glandular ERs	Number (%)	𝑃
A	12	5–30%	1 (8.3)		5–30%	0	n.s.
		30–60%	9 (75)		30–60%	4 (33.3)
		>60%	2 (16.7)	n.s.	>60%	8 (66.7)
B	10	5–30%	5 (50)		5–30%	0
		30–60%	5 (50)		30–60%	7 (70)
		>60%	0 (0)		>60%	3 (30)
Group	Total number	Stromal PRs intensity	Number (%)	𝑃	Glandular PRs intensity	Number (%)	𝑃
A	12	Low	1 (8.3)		Low	0 (0)	n.s.
		High	11 (91.7)	n.s.	High	12 (100)
B	10	Low	1 (10)		Low	(0)
		High	9 (90)		High	10 (100)
Group	Total number	Percentage of stromal PRs	Number (%)	𝑃	Percentage of glandular PRs	Number (%)	𝑃
A	12	5–30%	1 (8.3)		5–30%	0 (0)	n.s.
		30–60%	4 (33.3)		30–60%	1 (8.3)
		>60%	7 (58.3)	n.s.	>60%	11 (91.7)
B	10	5–30%	0 (0)		5–30%	0 (0)
		30–60%	7 (70)		30–60%	2 (20)
		>60%	3 (30)		>60%	8 (80)

ERs: estrogen receptors; PRs: progesterone receptors.