Cardiovascular Autonomic Neuropathy in Context of Other Complications of Type 2 Diabetes Mellitus

Table 3

Univariate logistic regression analysis (CAN+, CAN− patient groups).

Variable	Odds ratio	95% CI	P value
Male/Female	0.90	0.4682 to 1.7569	0.772
Age (years)	1.02	0.9864 to 1.0688	0.19
Age diabetes dg. (years)	0.89	0.8571 to 0.9402	<0,0001
Diabetes duration (years)	1.6797	1.4278 to 1.9760	0.0001
Body mass index (kg/m^2)	1.13	1.0588 to 1.2139	0.0003
SBP (mmHg)	1.01	1.0000 to 1.0360	0.05
DBP (mmHg)	1.0046	0.9710 to 1.0394	0.78
HT (yes)	1.56	0.7656 to 3.2024	0.21
SCORE	1.12	1.0425 to 1.2069	0.002
Smoking (yes versus no)	2.22	1.1327 to 4.3598	0.02
Severity of smoking (>20 versus <20 cigarettes/day)	1.29	0.4773 to 3.5148	0.6115
Cholesterol (mg%)	1.01	1.0041 to 1.0189	0.0023
Triglycerides (mg%)	1.0024	0.9999 to 1.0049	0.0633
HbA1c	1.83	1.3826 to 2.4302	<0.0001
Treatment of diabetes	3.0000	1.3458 to 6.6873	0.0072
FPG (mg%)	1.0061	1.0008 to 1.0115	0.02
eGFR (mL/min per 1.73 m^2)	0.90	0.8808 to 0.9376	<0.0001
ABI	0.0046	0.0002 to 0.0944	0.0005
QTC	1.05	1.0341 to 1.0728	<0.0001
IMT	12.48	8.21 to 18.32	<0.0001
Retinopathy (yes versus no)	16.5306	2.0342 to 134.3347	0.008
Peripheral neuropathy (yes versus no)	29.9444	12.0439 to 74.4503	0.0001

SBP: systolic blood pressure, DBP: diastolic blood pressure, HT: hypertension, SCORE: systematic coronary risk evaluation, HbA1c: glycosylated hemoglobin, FPG: fasting plasma glucose, eGFR: estimated glomerular filtration rate, ABI: ankle-brachial index, IMT: intima-media thickness, and QTC: corrected QT interval.