Research Article

Ovarian and Breast Cancer Spheres Are Similar in Transcriptomic Features and Sensitive to Fenretinide

Figure 2

Sphere cells from the ovarian cancer A2780 cell line were highly tumorigenic. (a) Tumor volume of injected mice was measured at indicated time point after the injection of 10000 sphere cells and the same number of parental cells. Means and standard errors of four mice were shown ( ). ***, statistically significant difference in mean tumor size between the mice injected with enriched sphere cells and mice injected with the same number of unenriched cells ( ). (b) Means and standard errors of tumors weight from four mice in each group were measured. *, statistically significant difference in mean tumor weight between two groups ( ).
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(a)
510905.fig.002b
(b)