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BioMed Research International
Volume 2013 (2013), Article ID 515712, 10 pages
http://dx.doi.org/10.1155/2013/515712
Research Article

Genotypically Different Clones of Staphylococcus aureus Are Diverse in the Antimicrobial Susceptibility Patterns and Biofilm Formations

1Laboratory of Medical Microbiology and Parasitology, Faculty of Medicine and Health Science, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
2Department of Medical Microbiology, Basrah University, Basrah, Iraq
3Laboratory of Marine Science and Aquaculture, Institute of Bioscience, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
4Department of Biomedical Sciences, Faculty of Medicine and Health Science, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
5Department of Biomedical Sciences, Faculty of Medicine and Health Science, Al Bukacyriyah, Saudi Arabia
6Department of Microbiology and Immunology, Arak University of Medical Sciences, Arak, Iran

Received 30 April 2013; Accepted 4 October 2013

Academic Editor: Javeed Iqbal

Copyright © 2013 Salman Sahab Atshan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Figure S1 (A): Linear regression analysis of MIC values for vancomycin, against both MRSA and MSSA isolates. (B): Linear regression analysis of MIC values for amoxicillin/clavulanic acid against both MRSA and MSSA isolates. (C): Linear regression analysis of MIC values for daptomycin against both MRSA and MSSA isolates. (D): Linear regression analysis of MIC values for linezolid against both MRSA and MSSA isolates. (E): Linear regression analysis of MIC values for tigecycline against both MRSA and MSSA isolates.

Figure S2: In-vitro activity of vancomycin, amoxicillin/clavulanic acid, linezolid, daptomycin and tigecycline against 20 sequence types of 30 MSSA(A) and 6 major sequence types of 30 MRSA isolates (B) prevalence in Malaysia.

Figure S3 (A): Vancomycin read at endpoint of MIC 1.00 and 0.75 μg/mL against MSSA-ATCC25643 and MRSA-ATCC43300 reference strain, respectively, using E test system. (B): Amoxicillin/clavulanic acid at endpoint of MIC 0.47 and 1.0 μg/mL against MSSA-ATCC25643 and MRSA-ATCC43300 reference strain, respectively, using E test system. (C): Linzolid read at endpoint of MIC 5.0 and 0.19 μg/mL against MSSA-ATCC25643 and MRSA-ATCC43300 reference strain, respectively, using E test system. (D): Daptomycin read at endpoint of MIC 0.64 and 0.64 μg/mL against MSSA-ATCC25643 and MRSA-ATCC43300 reference strain, respectively, using E test system. (E): Tigecycline read at endpoint of MIC 0.64 and 0.94 μg/mL against MSSA-ATCC25643 and MRSA-ATCC43300 reference strain, respective, using E test system.

Figure S4 (A): Linear regression analysis of MBC values for Vancomycin, against both MRSA and MSSA isolates. (B): Linear regression analysis of MBC values for linezolid against both MRSA and MSSA isolates. (C): Linear regression analysis of MBC values for tigecycline against both MRSA and MSSA isolates. (D): Linear regression analysis of MBC values for daptomycine against both MRSA and MSSA isolates. (E): Linear regression analysis of MBC values for amoxicillin/clavulanic acid against both MRSA and MSSA isolates.

  1. Supplementary Figures