Side Population Cells as Prototype of Chemoresistant, Tumor-Initiating Cells

Table 2

Multidrug resistance mediated by SP cells.

SP expressing cancers	Resistance to drugs	Ref.
Gastric cancer cell line SGC-7901	5-Fluorouracil cisplatin, 5-fluorouracil, doxorubicin	[18, 72]
Melanoma	Paclitaxel	[73]
Malignant pleural mesothelioma	Mitoxantrone	[50]
Head and neck squamous cell carcinoma	5-Fluorouracil mitoxantrone	[74, 75]
CLL	Fludarabine, bendamustine, or rituximab	[76]
Pancreatic carcinoma	Gemcitabine	[77, 78]
Nasopharyngeal	Mitoxantrone, cisplatin, mitomycin-C	[68]
Endometrial	Paclitaxel	[56]
Glioma	5-Fluorouracil and carboplatin	[79]
Breast	Paclitaxel, epirubicin, mitoxantrone, carboplatin	[80]
		[54]
Lung	Mitoxantrone, doxorubicin	[55]
Esophageal	5-Fluorouracil	[81]
Bladder	Mitomycin-C, mitoxantrone	[82]