Topical 100% Serum Eye Drops for Treating Corneal Epithelial Defect after Ocular Surgery

Table 3

Summary of 11 patients unresponsive to serum eye drops treatment.

Diagnosis	Indication	Number (%)	Increased dosage	Further treatment
Alkali injuries	Tectonic PK	1 (0.55)	100% ASE q 1 hr	AMT with tarsorrhaphy
Ocular cicatricial pemphigoid	Therapeutic PK	1 (0.55)	100% AlloSE q 1 hr	AMT with tarsorrhaphy
Severe fungal keratitis	Therapeutic PK	2 (1.10)	100% ASE q 1 hr	AMT (2), Gunderson conjunctival flap (1)
Stevens-Johnson syndrome
(i) Corneal ulcer failed medical therapy	Therapeutic PK	2 (1.10)	100% ASE q 1 hr	AMT with tarsorrhaphy (2)
(ii) Corneal melting and perforation	Therapeutic PK	2 (1.10)	100% ASE q 1 hr	AMT with tarsorrhaphy (1), evisceration (1)
(iii) Post-Boston keratoprosthesis surgery	Optical	3 (1.66)	100% ASE q 1 hr	Regraft, glue adhesion, and tarsorrhaphy (2), evisceration (1)

ASE: autologous serum eye drops; AlloSE: allogeneic serum eye drops; PK: penetrating keratoplasty; AMT: amniotic membrane transplantation.