- About this Journal
- Abstracting and Indexing
- Aims and Scope
- Annual Issues
- Article Processing Charges
- Articles in Press
- Author Guidelines
- Bibliographic Information
- Citations to this Journal
- Contact Information
- Editorial Board
- Editorial Workflow
- Free eTOC Alerts
- Publication Ethics
- Reviewers Acknowledgment
- Submit a Manuscript
- Subscription Information
- Table of Contents
BioMed Research International
Volume 2013 (2013), Article ID 524324, 9 pages
Estrogen Signaling through Estrogen Receptor Beta and G-Protein-Coupled Estrogen Receptor 1 in Human Cerebral Vascular Endothelial Cells: Implications for Cerebral Aneurysms
Australian School of Advanced Medicine, Macquarie University, 2 Technology Place, North Ryde, Sydney,
NSW 2109, Australia
Received 27 August 2013; Accepted 28 September 2013
Academic Editor: Robert M. Starke
Copyright © 2013 Jian Tu and Nurul F. Jufri. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- W. T. Longstreth Jr., L. M. Nelson, T. D. Koepsell, and G. van Belle, “Subarachnoid hemorrhage and hormonal factors in women: a population-based case-control study,” Annals of Internal Medicine, vol. 121, no. 3, pp. 168–173, 1994.
- M. S. Ali, R. M. Starke, P. M. Jabbour, S. I. Tjoumakaris, L. F. Gonzalez, R. H. Rosenwasser, et al., “TNF-a induces phenotypic modulation in cerebral vascular smooth muscle cells: implications for cerebral aneurysm pathology,” Journal of Cerebral Blood Flow & Metabolism, vol. 33, pp. 1564–1573, 2013.
- N. Chalouhi, M. S. Ali, P. M. Jabbour, et al., “Biology of intracranial aneurysms: role of inflammation,” Journal of Cerebral Blood Flow & Metabolism, vol. 32, no. 9, pp. 1659–1676, 2012.
- Y. Kanematsu, M. Kanematsu, C. Kurihara et al., “Critical roles of macrophages in the formation of intracranial aneurysm,” Stroke, vol. 42, no. 1, pp. 173–178, 2011.
- S. E. Francis, J. Tu, Y. Qian, and A. P. Avolio, “A combination of genetic, molecular and haemodynamic risk factors contribute to the formation, enlargement and rupture of brain aneurysms,” Journal of Clinical Neuroscience, vol. 20, no. 7, pp. 912–918, 2013.
- P. E. Norman and J. T. Powell, “Site specificity of aneurysmal disease,” Circulation, vol. 121, no. 4, pp. 560–568, 2010.
- R. E. de Meersman, A. S. Zion, E. G. V. Giardina, J. P. Weir, J. S. Lieberman, and J. A. Downey, “Estrogen replacement, vascular distensibility, and blood pressures in postmenopausal women,” American Journal of Physiology—Heart and Circulatory Physiology, vol. 274, no. 5, pp. H1539–H1544, 1998.
- R. Stricker, R. Eberhart, M.-C. Chevailler, F. A. Quinn, P. Bischof, and R. Stricker, “Establishment of detailed reference values for luteinizing hormone, follicle stimulating hormone, estradiol, and progesterone during different phases of the menstrual cycle on the Abbott ARCHITECT analyzer,” Clinical Chemistry and Laboratory Medicine, vol. 44, no. 7, pp. 883–887, 2006.
- C. J. Gruber, W. Tschugguel, C. Schneeberger, and J. C. Huber, “Mechanisms of disease: production and actions of estrogens,” The New England Journal of Medicine, vol. 346, no. 5, pp. 340–352, 2002.
- N. Heldring, A. Pike, S. Andersson et al., “Estrogen receptors: how do they signal and what are their targets,” Physiological Reviews, vol. 87, no. 3, pp. 905–931, 2007.
- E. R. Prossnitz, J. B. Arterburn, H. O. Smith, T. I. Oprea, L. A. Sklar, and H. J. Hathaway, “Estrogen signaling through the transmembrane G protein-coupled receptor GPR30,” Annual Review of Physiology, vol. 70, pp. 165–190, 2008.
- R. C. Tostes, D. Nigro, Z. B. Fortes, and M. H. C. Carvalho, “Effects of estrogen on the vascular system,” Brazilian Journal of Medical and Biological Research, vol. 36, no. 9, pp. 1143–1158, 2003.
- S. Liu, V. Sammons, J. Fairhall, et al., “Molecular responses of brain endothelial cells to radiation,” Journal of Clinical Neuroscience, vol. 19, no. 8, pp. 1154–1158, 2012.
- J. L. Hintze, “Analysis of variance,” in Number Cruncher Statistical Systems (NCSS) 97-User’s Guide-I, pp. 205–278, NCSS, Kaysville, Utah, USA, 1997.
- C. Stirone, S. P. Duckles, and D. N. Krause, “Multiple forms of estrogen receptor-α in cerebral blood vessels: regulation by estrogen,” American Journal of Physiology—Endocrinology and Metabolism, vol. 284, no. 1, pp. E184–E192, 2003.
- B. J. Deroo and K. S. Korach, “Estrogen receptors and human disease,” Journal of Clinical Investigation, vol. 116, no. 3, pp. 561–570, 2006.
- E. R. Prossnitz and M. Barton, “The G-protein-coupled estrogen receptor GPER in health and disease,” Nature Reviews Endocrinology, vol. 7, no. 12, pp. 715–726, 2011.
- P. Thomas, Y. Pang, E. J. Filardo, and J. Dong, “Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells,” Endocrinology, vol. 146, no. 2, pp. 624–632, 2005.
- C. M. Revankar, D. F. Cimino, L. A. Sklar, J. B. Arterburn, and E. R. Prossnitz, “A transmembrane intracellular estrogen receptor mediates rapid cell signaling,” Science, vol. 307, no. 5715, pp. 1625–1630, 2005.
- F. Gobeil Jr., A. Fortier, T. Zhu et al., “G-protein-coupled receptors signalling at the cell nucleus: an emerging paradigm,” Canadian Journal of Physiology and Pharmacology, vol. 84, no. 3-4, pp. 287–297, 2006.
- E. R. Prossnitz, J. B. Arterburn, and L. A. Sklar, “GPR30: a G protein-coupled receptor for estrogen,” Molecular and Cellular Endocrinology, vol. 265-266, pp. 138–142, 2007.
- E. J. Filardo, J. A. Quinn, A. Raymond Frackelton Jr., and K. I. Bland, “Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis,” Molecular Endocrinology, vol. 16, no. 1, pp. 70–84, 2002.
- N. Kanda and S. Watanabe, “17β-estradiol inhibits oxidative stress-induced apoptosis in keratinocytes by promoting Bcl-2 expression,” Journal of Investigative Dermatology, vol. 121, no. 6, pp. 1500–1509, 2003.
- N. Kanda and S. Watanabe, “17β-estradiol enhances the production of nerve growth factor in THP-1-derived macrophages or peripheral blood monocyte-derived macrophages,” Journal of Investigative Dermatology, vol. 121, no. 4, pp. 771–780, 2003.
- N. Kanda and S. Watanabe, “17β-estradiol stimulates the growth of human keratinocytes by inducing cyclin D2 expression,” Journal of Investigative Dermatology, vol. 123, no. 2, pp. 319–328, 2004.
- M. Maggiolini, A. Vivacqua, G. Fasanella et al., “The G protein-coupled receptor GPR30 Mediates c-fos up-regulation by 17β-estradiol and phytoestrogens in breast cancer cells,” Journal of Biological Chemistry, vol. 279, no. 26, pp. 27008–27016, 2004.
- E. J. Filardo, J. A. Quinn, K. I. Bland, and A. R. Frackelton Jr., “Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF,” Molecular Endocrinology, vol. 14, no. 10, pp. 1649–1660, 2000.
- E. Brailoiu, S. L. Dun, G. C. Brailoiu et al., “Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system,” Journal of Endocrinology, vol. 193, no. 2, pp. 311–321, 2007.
- F. Edwin, G. J. Wiepz, R. Singh et al., “A historical perspective of the EGF receptor and related systems,” Methods in Molecular Biology, vol. 327, pp. 1–24, 2006.
- E. J. Filardo and P. Thomas, “GPR30: a seven-transmembrane-spanning estrogen receptor that triggers EGF release,” Trends in Endocrinology and Metabolism, vol. 16, no. 8, pp. 362–367, 2005.
- M. R. Meyer, E. Haas, E. R. Prossnitz, and M. Barton, “Non-genomic regulation of vascular cell function and growth by estrogen,” Molecular and Cellular Endocrinology, vol. 308, no. 1-2, pp. 9–16, 2009.
- N. F. Jufri, M. Baker, and J. Tu, “Estrogen deficiency reduces cellular structural protein synthesis in a cell model of aneurysm in menopausal and postmenopausal women,” in Proceedings of the Asia Pacific Stroke Conference, Hong Kong, China, August-September 2013.
- M. Chen, B. Ouyang, L. Goldstein-Smith, and L. Feldman, “Oral contraceptive and hormone replacement therapy in women with cerebral aneurysms,” Journal of NeuroInterventional Surgery, vol. 3, no. 2, pp. 163–166, 2011.
- M. A. Jamous, S. Nagahiro, K. T. Kitazato, T. Tamura, K. Kuwayama, and K. Satoh, “Role of estrogen deficiency in the formation and progression of cerebral aneurysms. Part II: experimental study of the effects of hormone replacement therapy in rats,” Journal of Neurosurgery, vol. 103, no. 6, pp. 1052–1057, 2005.