Research Article
CYP3A5*3 and C3435T MDR1 Polymorphisms in Prognostication of Drug-Resistant Epilepsy in Children and Adolescents
Table 2
Genotypes of C3435T MDR1 in study groups and drug resistance of epilepsy.
| | Genotype | Number of patients | Control group [100%] | | Drug resistant [100%] | Drug responsive [100%] |
| | CC | 9 (15.0%) | 1 (4.0%) | 21 (21.0%) | | CT | 33 (55.0%) | 16 (64.0%) | 51 (51.0%) | | TT | 18 (30.0%) | 8 (32.0%) | 28 (28.0%) | Comparison of groups of patients with epilepsy
(genotypes CC, CT, and TT versus other genotypes together) |
NS
CC (). CT ()
TT () | — | Comparisons with control group
(genotypes CC, CT, and TT versus other genotypes together) | NS
CC ()
CT ()
TT () | NS
CC ()
CT ()
TT () | — | | Hardy-Weinberg equilibrium | Maintained
() | Maintained
() | — |
|
|
NS: not statistically significant.
|
