Table 1: Relationship between the expression of MRP2 in GBCA and clinicopathological characteristics.

CharacteristicsTotalMRP2 expression
Positive (%)Negative (%) value

Age (year-old)
 ≥647142 (59.2)29 (40.8) 0.153
 <647234 (47.2)38 (52.8)
Sex
 Man7038 (54.3)32 (45.7) 0.789
 Woman7338 (52.1)35 (47.9)
Histologic grade
 1 (well differentiated)5629 (51.8)27 (48.2)
 2 (moderately differentiated)6638 (57.6)28 (42.4)0.736
 3 (poorly differentiated)219 (42.9)12 (57.1)
Tumor size (cm)
 ≥2.57238 (52.8)34 (47.2) 0.929
 <2.57138 (53.5)33 (46.5)
Pathological T stage
 pT1239 (39.1)14 (60.9)
 pT28047 (58.8)33 (41.3) 0.743
 pT32814 (50.0)14 (50.0)
 pT4126 (50.0)6 (50.0)
Nodal metastasis
 Present5026 (52.0)24 (48.0)
 Absent8347 (56.6)36 (43.4)0.604
 Unknown10
Distant metastasis
 Present2513 (52.0)12 (48.0) 0.899
 Absent11863 (53.4)55 (46.6)
TNM Stage
 I176 (35.3)11 (64.7)
 II4329 (52.4)14 (32.6)
 III6333 (52.4)30 (47.6)0.868
 IV105 (50.0)5 (50.0)
 Unknown10
Local recurrence
 Present2518 (72.0)7 (28.0) 0.038*
 Absent11858 (49.2)60 (50.8)
Lymphatic invasion
 Present6038 (63.3)22 (36.7) 0.038*
 Absent8338 (45.8)45 (54.2)
Vascular invasion
 Present3625 (69.4)11 (30.6) 0.023*
 Absent10751 (47.7)56 (52.3)
Perineural invasion
 Present2922 (75.9)7 (24.1) 0.006*
 Absent11454 (47.4)60 (52.6)
Resection margin involvement
 Present1710 (58.8)7 (41.2) 0.617
 Absent12666 (52.4)60 (47.6)

Statistically significant.