Does the Adult Human Ciliary Body Epithelium Contain “True” Retinal Stem Cells?

Table 1

Comparison of gene expression profile of four key neural stem cell (NSC) markers.

Gene	WT CE	CE spheres	PVR spheres	SVZ spheres
GFAP	−	−/+	++	+++
Sox-2	−	+	+	++
Nestin	+	+	+	++
Nanog	+	+	+	+

Semiquantitative comparison of RT-PCR expression in adult human ciliary body epithelium (CE) whole tissue samples (WT CE) [32] and cultivated spheres from the adult human CE [32], proliferative vitreoretinopathy (PVR) samples [33], and subventricular zone (SVZ) biopsies [34]. No detectable expression: (−), very low: (−/+), low: (+), middle: (++), and high: (+++) expression.