Allergy or Tolerance: Reduced Inflammatory Cytokine Response and Concomitant IL-10 Production of Lymphocytes and Monocytes in Symptom-Free Titanium Dental Implant Patients
Figure 2
Lymphocyte proliferation response of the PBMC of the 14 healthy individuals without titanium dental implants (open bar) and 6 blood donors with symptom-free titanium dental implants (closed bar). Reactivity to stimulation with titanium particles in rutile and anatase structures (5 × 10−4 M, 1 × 10−4 M, 5 × 10−5 M) ((a) and (b)), the three titanium metal discs (SBA, MA, and SA) (c) and to the controls (recall antigen) tetanus toxoid (TT) and (pan T cell mitogen) phytohemagglutinin (PHA), over 6 days. Stimulation index (SI) is given as ratio of stimulated culture to unstimulated culture.
