Review Article
Candidate Genes for Proliferative Diabetic Retinopathy
Table 6
The reported studies of adhesion molecules (ICAM, PECAM, VCAM) and proliferative diabetic retinopathy in subjects with type 2 diabetes.
| | Population | Subjects with type 2 diabetes (n) | Polymorphism (rs) | Risk genotype/allele | OR (P value)1 | Reference |
| | Chinese population | 172 (PDR versus NDR versus dm without DR) | ICAM-12-K469E
ICAM-12-G241A | K allele;
no association | NA (0.01);
NA | [64] | | Slovene population (Caucasians) | 338 (PDR versus dm without DR) | ICAM-12-K469E
ICAM-12-G241A | EE;
no association | 2.0 (0.01);
NA | [18] |
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1Odds ratio and P value in logistic regression analysis; 2intracellular adhesion molecule-1.
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