Table 5: Amino acid residue changes mapped into B-cell epitopes. The amino acids in bold and italic are the positions of change in the predicted B-cell epitopes.

L1 epitopes prediction for B-cellAmino acid change insered in epitope sequence

TCQKDQP PPEKQDPLSKYKFWEVP430S
EYQIFNKPYWLQ RAQGQNNGIQ313H
VDTTRSTNLT T337S
NE LFVTVVDTTE329D
AE YKATNFREFLRHTEEFDLQE354D
LQFIFQLCKIQ LTPEQ382R
CQKDAPT PEKKDPYDDLKFT433A