Identification and Biotechnological Application of Novel Regulatory Genes Involved in Streptomyces Polyketide Overproduction through Reverse Engineering Strategy
Figure 1
Time-dependent ACT volumetric productivities of wild-type S. coelicolor M145 (♦), S. coelicolor ΔwblA (■), S. coelicolor ΔwblAΔSCO1712 (▲), and S. coelicolor ΔwblAΔSCO1712Δ5426 (●) cultured in modified R5 media during 9 days in a 2-liter bioreactor [16].