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BioMed Research International
Volume 2013 (2013), Article ID 561410, 8 pages
In Vitro Construction of Scaffold-Free Bilayered Tissue-Engineered Skin Containing Capillary Networks
1Department of Oral Histology and Pathology, School of Stomatology, The Fourth Military Medical University, Xi'an 710032, China
2Xi'an Institute of Tissue Engineering & Regenerative Medicine, Xi'an 710032, China
3Department of Periodontology & Oral Medicine, School of Stomatology, The Fourth Military Medical University, Xi'an 710032, China
4Department of Anatomy, Osaka Dental University, 8-1 Kuzuhahanazono-cho, Hirakata-shi, Osaka 573-1121, Japan
5Department of Dental Oriental Medicine, Osaka Dental University, 8-1 Kuzuhahanazono-cho, Hirakata-shi, Osaka 573-1121, Japan
Received 5 January 2013; Revised 21 February 2013; Accepted 22 February 2013
Academic Editor: Richard Tucker
Copyright © 2013 Yuan Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- M. Chen, M. Przyborowski, and F. Berthiaume, “Stem cells for skin tissue engineering and wound healing,” Critical Reviews in Biomedical Engineering, vol. 37, no. 4-5, pp. 399–421, 2009.
- S. MacNeil, “Progress and opportunities for tissue-engineered skin,” Nature, vol. 445, no. 7130, pp. 874–880, 2007.
- B. Hendrickx, J. J. Vranckx, and A. Luttun, “Cell-based vascularization strategies for skin tissue engineering,” Tissue Engineering Part B, vol. 17, no. 1, pp. 13–24, 2011.
- A. D. Metcalfe and M. W. J. Ferguson, “Tissue engineering of replacement skin: the crossroads of biomaterials, wound healing, embryonic development, stem cells and regeneration,” Journal of the Royal Society Interface, vol. 4, no. 14, pp. 413–417, 2007.
- D. M. Supp and S. T. Boyce, “Engineered skin substitutes: practices and potentials,” Clinics in Dermatology, vol. 23, no. 4, pp. 403–412, 2005.
- A. Siddiqui, R. D. Galiano, D. Connors, E. Gruskin, L. Wu, and T. A. Mustoe, “Differential effects of oxygen on human dermal fibroblasts: acute versus chronic hypoxia,” Wound Repair and Regeneration, vol. 4, no. 2, pp. 211–218, 1996.
- P. S. Sahota, J. L. Burn, M. Heaton et al., “Development of a reconstructed human skin model for angiogenesis,” Wound Repair and Regeneration, vol. 11, no. 4, pp. 275–284, 2003.
- A. H. Zisch, M. P. Lutolf, and J. A. Hubbell, “Biopolymeric delivery matrices for angiogenic growth factors,” Cardiovascular Pathology, vol. 12, no. 6, pp. 295–310, 2003.
- A. H. Zisch, M. P. Lutolf, M. Ehrbar et al., “Cell-demanded release of VEGF from synthetic, biointeractive cell ingrowth matrices for vascularized tissue growth,” FASEB Journal, vol. 17, no. 15, pp. 2260–2262, 2003.
- J. Andrae, R. Gallini, and C. Betsholtz, “Role of platelet-derived growth factors in physiology and medicine,” Genes and Development, vol. 22, no. 10, pp. 1276–1312, 2008.
- T. Kitajima, H. Terai, and Y. Ito, “A fusion protein of hepatocyte growth factor for immobilization to collagen,” Biomaterials, vol. 28, no. 11, pp. 1989–1997, 2007.
- S. W. Spiekstra, M. Breetveld, T. Rustemeyer, R. J. Scheper, and S. Gibbs, “Wound-healing factors secreted by epidermal keratinocytes and dermal fibroblasts in skin substitutes,” Wound Repair and Regeneration, vol. 15, no. 5, pp. 708–717, 2007.
- S. Dickens, P. Vermeulen, B. Hendrickx, S. Van Den Berge, and J. J. Vranckx, “Regulable vascular endothelial growth factor165 overexpression by ex vivo expanded keratinocyte cultures promotes matrix formation, angiogenesis, and healing in porcine full-thickness wounds,” Tissue Engineering Part A, vol. 14, no. 1, pp. 19–27, 2008.
- P. S. Sahota, J. L. Burn, N. J. Brown, and S. MacNeil, “Approaches to improve angiogenesis in tissue-engineered skin,” Wound Repair and Regeneration, vol. 12, no. 6, pp. 635–642, 2004.
- M. Lovett, K. Lee, A. Edwards, and D. L. Kaplan, “Vascularization strategies for tissue engineering,” Tissue Engineering Part B, vol. 15, no. 3, pp. 353–370, 2009.
- S. Chaterji, K. Park, and A. Panitch, “Scaffold-free in vitro arterial mimetics: the importance of smooth muscle-endothelium contact,” Tissue Engineering Part A, vol. 16, no. 6, pp. 1901–1912, 2010.
- D. F. Williams, “On the mechanisms of biocompatibility,” Biomaterials, vol. 29, no. 20, pp. 2941–2953, 2008.
- J. M. Kelm and M. Fussenegger, “Scaffold-free cell delivery for use in regenerative medicine,” Advanced Drug Delivery Reviews, vol. 62, no. 7-8, pp. 753–764, 2010.
- D. Y. Lee, J. H. Lee, J. M. Yang, E. S. Lee, K. H. Park, and G. H. Mun, “A new dermal equivalent: the use of dermal fibroblast culture alone without exogenous materials,” Journal of Dermatological Science, vol. 43, no. 2, pp. 95–104, 2006.
- B. S. Yoon, S. J. Yoo, J. E. Lee, S. You, H. T. Lee, and H. S. Yoon, “Enhanced differentiation of human embryonic stem cells into cardiomyocytes by combining hanging drop culture and 5-azacytidine treatment,” Differentiation, vol. 74, no. 4, pp. 149–159, 2006.
- L. A. Kunz-Schughart, J. A. Schroeder, M. Wondrak et al., “Potential of fibroblasts to regulate the formation of three-dimensional vessel-like structures from endothelial cells in vitro,” American Journal of Physiology, vol. 290, no. 5, pp. C1385–C1398, 2006.
- D. Knight, “Epithelium-fibroblast interactions in response to airway inflammation,” Immunology and Cell Biology, vol. 79, no. 2, pp. 160–164, 2001.
- M. Nomi, A. Atala, P. De Coppi, and S. Soker, “Principals of neovascularization for tissue engineering,” Molecular Aspects of Medicine, vol. 23, no. 6, pp. 463–483, 2002.
- A. Gaspar, L. Moldovan, D. Constantin, A. M. Stanciuc, P. M. Sarbu Boeti, and I. C. Efrimescu, “Collagen-based scaffolds for skin tissue engineering,” Journal of Medicine and Life, vol. 4, no. 2, pp. 172–177, 2011.
- M. W. Laschke, Y. Harder, M. Amon et al., “Angiogenesis in tissue engineering: breathing life into constructed tissue substitutes,” Tissue Engineering, vol. 12, no. 8, pp. 2093–2104, 2006.
- P. L. Tremblay, V. Hudon, F. Berthod, L. Germain, and F. A. Auger, “Inosculation of tissue-engineered capillaries with the host's vasculature in a reconstructed skin transplanted on mice,” American Journal of Transplantation, vol. 5, no. 5, pp. 1002–1010, 2005.
- A. Wenger, N. Kowalewski, A. Stahl et al., “Development and characterization of a spheroidal coculture model of endothelial cells and fibroblasts for improving angiogenesis in tissue engineering,” Cells Tissues Organs, vol. 181, no. 2, pp. 80–88, 2006.
- D. Ruiter, T. Bogenrieder, D. Elder, and M. Herlyn, “Melanoma-stroma interactions: structural and functional aspects,” The Lancet Oncology, vol. 3, no. 1, pp. 35–43, 2002.
- L. P. Kamolz, M. Luegmair, N. Wick et al., “The Viennese culture method: cultured human epithelium obtained on a dermal matrix based on fibroblast containing fibrin glue gels,” Burns, vol. 31, no. 1, pp. 25–29, 2005.
- W. Friess, “Collagen—biomaterial for drug delivery,” European Journal of Pharmaceutics and Biopharmaceutics, vol. 45, no. 2, pp. 113–136, 1998.
- P. M. Royce, T. Kato, K. I. Ohsaki, and A. Miura, “The enhancement of cellular infiltration and vascularisation of a collagenous dermal implant in the rat by platelet-derived growth factor BB,” Journal of Dermatological Science, vol. 10, no. 1, pp. 42–52, 1995.
- Y. M. Elçin, V. Dixit, and G. Gitnick, “Extensive in vivo angiogenesis following controlled release of human vascular endothelial cell growth factor: implications for tissue engineering and wound healing,” Artificial Organs, vol. 25, no. 7, pp. 558–565, 2001.
- R. K. Schneider, J. Anraths, R. Kramann et al., “The role of biomaterials in the direction of mesenchymal stem cell properties and extracellular matrix remodelling in dermal tissue engineering,” Biomaterials, vol. 31, no. 31, pp. 7948–7959, 2010.
- D. G. Chalupowicz, Z. A. Chowdhury, T. L. Bach, C. Barsigian, and J. Martinez, “Fibrin II induces endothelial cell capillary tube formation,” Journal of Cell Biology, vol. 130, no. 1, pp. 207–215, 1995.
- D. E. Ingber and J. Folkman, “Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: role of extracellular matrix,” Journal of Cell Biology, vol. 109, no. 1, pp. 317–330, 1989.
- Y. Kubota, H. K. Kleinman, G. R. Martin, and T. J. Lawley, “Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structures,” Journal of Cell Biology, vol. 107, no. 4, pp. 1589–1598, 1988.
- C. Norotte, F. S. Marga, L. E. Niklason, and G. Forgacs, “Scaffold-free vascular tissue engineering using bioprinting,” Biomaterials, vol. 30, no. 30, pp. 5910–5917, 2009.
- A. C. Newman, M. N. Nakatsu, W. Chou, P. D. Gershon, and C. C. Hughes, “The requirement for fibroblasts in angiogenesis: fibroblast-derived matrix proteins are essential for endothelial cell lumen formation,” Molecular Biology of the Cell, vol. 22, no. 20, pp. 3791–3800, 2011.
- G. Jin, M. P. Prabhakaran, and S. Ramakrishna, “Stem cell differentiation to epidermal lineages on electrospun nanofibrous substrates for skin tissue engineering,” Acta Biomaterialia, vol. 7, no. 8, pp. 3113–3122, 2011.
- G. Galassi, P. Brun, M. Radice et al., “In vitro reconstructed dermis implanted in human wounds: degradation studies of the HA-based supporting scaffold,” Biomaterials, vol. 21, no. 21, pp. 2183–2191, 2000.