Aminopeptidase N (CD13) Is Involved in Phagocytic Processes in Human Dendritic Cells and Macrophages
Figure 6
CD13 cross-linking does not modulate cytokine secretion induced by peptidoglycan from S. aureus. Human MD-DCs (gray bars) or MD-Ms (black bars) were stimulated with 10 μg of anti-CD13 mAb 452, or with 10 μg F(ab′)2 fragments of anti-CD13 mAb plus secondary antibody, in the presence or absence of 10 μg PGN. After 18 h at 37°C, cells’ supernatants were collected and assayed for the presence of IL-6, IL-10, IL-12, or TNFα using ELISA. Data shown are the average ± SD of three independent experiments with cells from three different donors.
