Table 3: Models to ascertain the kinetic of drug release.

Mathematical modelEquation

Zero order
First order
Higuchi
Hixson-Crowell
Korsmeyer-Peppas

: amount of drug released in time ; : initial amount of drug in the dosage form; : total amount of drug dissolved when the dosage form is exhausted; , , , , : release rate constants; : release exponent (indicative of drug release mechanism).