Research Article

Development of a Modelling to Correlate Site and Diameter of Brain Metastases with Hippocampal Sparing Using Volumetric Modulated Arc Therapy

Table 1

Parameters of 15 RA plans.

PlanDiameter (cm)Mean Hippocampal Dose (Gy)Mean Hippocampal dose (Gy2)HI-PTV whole brainTC-PTV metastasesTC-PTV whole brain

DS 11 12.558.900.340.520.82
F 1113.9510.220.360.510.92
O 1112.829.150.640.540.99
P 1113.259.550.470.540.91
T 1136.1033.90.550.530.96
DS 2213.469.750.780.550.92
F 2213.499.780.780.720.90
O 2213.689.960.530.520.92
P 2214.8711.120.570.540.93
T 2242.0040.270.680.480.90
DS 3317.8014.180.770.490.93
F 3315.45 11.70 0.900.420.91
O 3313.669.940.600.510.93
P 3314.7611.010.840.460.93
T 3350.447.160.850.520.80

DS: deep structure; F: frontal lobe; O: occipital lobe; P: parietal lobe; T: temporal lobe; 1–3: metastases diameter (cm).