Table 5: ANN results showing (a) data training diagnostics, (b) the best network run, (c) the ANN model fit parameters and, (d) combination of polymers to produce the optimum .
(a)

All runsTraining
minimum
Training standard
deviation

Average of minimum MSEs 0.0160.0059
Average of final MSEs0.0160.0059

(b)

Best networkTraining

Run number2
Epoch number1000
Minimum MSE0.0098
Final MSE0.098

(c)

Performance

MSE
NMSE0.056
MAE0.0015
Min abs error0.00011
Max abs error0.0053
Correlation coefficient 0.98

(d)

Sodium bicarbonate
Drug PolymerPolymerRatioQuantityHBL1 HBL2

THPHECEC1 : 3
DTZHECEC1 : 1100

HBL1: HPMC middle barrier layer.
2HBL2: HPMC outer barrier layer.