Intravenous Transplantation of Mesenchymal Stromal Cells to Enhance Peripheral Nerve Regeneration
Figure 2
Longitudinal sections and immunohistology of sciatic nerve after peripheral nerve crush injury and intravenous transplantation of PKH-labelled MSCs. (a) and (b) Demonstration of axonal regeneration after peripheral nerve injury and cell transplantation: regenerated axons are stained with neurofilament (green) in low and higher magnifications. (c) and (d) Distribution of i.v. transplanted PKH-labelled MSCs (red) and homing effect into the lesioned and subconsequent regenerated nerve fibers in relation to the neurofilament stained axons and endogenous cells stained with DAPI present within the nerve (blue).
