Cytokeratin 18 Is Not Required for Morphogenesis of Developing Prostates but Contributes to Adult Prostate Regeneration
Figure 3
Normal basal and luminal cell compartments in CK18−/− prostates. Immunofluorescence staining of prostate frozen sections displays similar luminal and basal cell compartments in WT (a) and CK18−/− (b) prostates. Luminal cells are positive for AR, CK8, and CK18, while the basal cells are CK5 and P63 positive. At least 4 mice were sacrificed in each group for prostate collection, sectioning, and staining. Multiple fields were thoroughly examined under a microscope. Representative images are shown. Pictures were taken using a Nikon fluorescent microscope (Nikon Eclipse Ti) with 400x magnification. Scale bars are 50 μm for each related row.
