Cytokeratin 18 Is Not Required for Morphogenesis of Developing Prostates but Contributes to Adult Prostate Regeneration

Figure 4

CK18 is dispensable for prostate branching. (a) The gross anatomic appearance of WT and CK18^−/− prostates with AP, VP, and DLP. Scale bars are 2000 μm. (b, c) The microdissection images display the ductal networks of prostate in left or right lobe of AP, VP, and DLP from WT and CK18^−/− mice (a). Four mice of each group are used in the experiment. Only representative pictures are shown. Scale bar for AP image is 2000 μm, in VP and DLP images is 1000 μm. (d, e) Bar graph shows no significant differences of ductal tips and branch points in AP, VP, and DLP between WT and of CK18^−/− prostates (𝑛=4).

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