Research Article

[Retracted] The Effects of Cytokines in Adipose Stem Cell-Conditioned Medium on the Migration and Proliferation of Skin Fibroblasts In Vitro

Figure 4

The effects of 50% ASC-CM with different concentrations of cytokines on proliferation of skin fibroblasts. The proliferation of fibroblasts was obviously promoted by EGF at 50 and 100 ng/mL (a) and also by bFGF at 20, 50, and 100 ng/mL (b), and their promoting effects were both inhibited by their neutralizing antibodies. However, PDGF and VEGF might not significantly contribute to fibroblasts proliferation (c and d). In addition, the promoting effect of 50% ASC-CM on fibroblasts proliferation was more significant than that of the control group (not containing ASC-CM) and each single cytokine. *( ); **( ); NA: neutralizing antibody group.
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(a)
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(b)
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(c)
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(d)