Review Article
Expression Systems and Species Used for Transgenic Animal Bioreactors
Table 1
Comparison of the different systems used to produce recombinant pharmaceutical proteins.
| ā | Bacteria | Mammalian cells | Transgenic animals |
| Production level | ++ | + | ++++ | Investment cost | +++++ | + | +++ | Production cost | +++++ | ++ | ++++ | Scaling-up ability | +++++ | + | ++++ | Collection | +++++ | +++++ | ++++ | Purification | +++ | ++++ | +++ | Posttranslational modifications | + | ++++ | ++++ | Glycosylation | + | ++++ | ++++ | Stability of product | +++++ | +++ | ++++ | Contaminant pathogens | +++++ | ++++ | ++++ | Products on the market | ++++ | +++++ | +++ |
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Table adapted from [1].
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